(S)-α-methylbenzyl methacrylate

Base Information

• Chemical Name: (S)-α-methylbenzyl methacrylate
• CAS No.: 17469-93-1
• Molecular Formula: C₁₂H₁₄O₂
• Molecular Weight: 190.242
• Mol file: 17469-93-1.mol

Synonyms:(S)-α-methylbenzyl methacrylate

Chemical Property of (S)-α-methylbenzyl methacrylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-α-methylbenzyl methacrylate

There total 4 articles about (S)-α-methylbenzyl methacrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-Phenylethanol (98-85-1,13323-81-4) + 2,3-butanedione mono-oxime methacrylate → (S)-1-phenylethanol (1445-91-6) + (R)-1-phenylethanol (1517-69-7) + (S)-α-methylbenzyl methacrylate (17469-93-1,4511-55-1) + (R)-α-methylbenzyl methacrylate (17199-94-9,4511-55-1)

Guidance literature:

With Pseudomonas cepacia lipase; In chloroform; at 30 ℃; for 55h; Title compound not separated from byproducts;

DOI:10.1055/s-2000-6493

Reference yield:

(S)-1-phenylethanol (1445-91-6) + Methacryloyl chloride (920-46-7,26937-45-1) → (S)-α-methylbenzyl methacrylate (17469-93-1,4511-55-1)

Guidance literature:

With pyridine;

DOI:10.1021/ja01541a038

Reference yield:

1-phenylethyl methacrylate (19321-42-7,4511-55-1) → (S)-α-methylbenzyl methacrylate (17469-93-1,4511-55-1) + (R)-α-methylbenzyl methacrylate (17199-94-9,4511-55-1)

Guidance literature:

With sparteine; cyclohexylmagnesium bromide; In toluene; at -78 ℃; for 2h; Product distribution; enantiomer-selective polymerization; activity and selectivity of a series of catalysts (grignard reagent-(-)-sparteine derivative); no selectivity for other anionic initiator in the presence of (-)-sparteine and (-)-α-isosparteine; mechanism discussed;

DOI:10.1021/ja00381a019

upstream raw materials:

(S)-1-phenylethanol

Methacryloyl chloride

1-phenylethyl methacrylate

1-Phenylethanol