2-Propenoic acid, 2-methyl-, 1-phenylethyl ester

Base Information

• Chemical Name: 2-Propenoic acid, 2-methyl-, 1-phenylethyl ester
• CAS No.: 19321-42-7
• Molecular Formula: C12H14O2
• Molecular Weight: 190.242
• DSSTox Substance ID: DTXSID00440705
• Nikkaji Number: J47.845H
• Mol file: 19321-42-7.mol

Synonyms:19321-42-7;2-Propenoic acid, 2-methyl-, 1-phenylethyl ester;a-methylbenzyl methacrylate;SCHEMBL41864;alpha-methylbenzyl methacrylate;DTXSID00440705;Methacrylic acid 1-phenylethyl ester

Chemical Property of 2-Propenoic acid, 2-methyl-, 1-phenylethyl ester

Chemical Property:

• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 190.099379685
• Heavy Atom Count: 14
• Complexity: 214

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C1=CC=CC=C1)OC(=O)C(=C)C

Technology Process of 2-Propenoic acid, 2-methyl-, 1-phenylethyl ester

There total 2 articles about 2-Propenoic acid, 2-methyl-, 1-phenylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

1-Phenylethanol (98-85-1,13323-81-4) + Methacryloyl chloride (920-46-7,26937-45-1) → 1-phenylethyl methacrylate (19321-42-7,4511-55-1)

Guidance literature:

With triethylamine; at 0 ℃; Inert atmosphere; Microwave irradiation;

DOI:10.2478/s11532-011-0046-2

Reference yield:

poly(methacrylic acid) (79-41-4,25087-26-7,50867-57-7) + 1-Phenylethanol (98-85-1,13323-81-4) → 1-phenylethyl methacrylate (19321-42-7,4511-55-1)

Guidance literature:

With toluene-4-sulfonic acid; hydroquinone; In benzene; for 9h; Yield given; Heating;

Reference yield:

3-acetylamino-2-ethylquinazolin-4(3H)-one (6761-24-6) + 1-phenylethyl methacrylate (19321-42-7,4511-55-1) → (S)-1-(2-Ethyl-4-oxo-4H-quinazolin-3-yl)-2-methyl-aziridine-2-carboxylic acid (S)-1-phenyl-ethyl ester + (S)-1-(2-Ethyl-4-oxo-4H-quinazolin-3-yl)-2-methyl-aziridine-2-carboxylic acid (R)-1-phenyl-ethyl ester

Guidance literature:

With 1,1,1,3,3,3-hexamethyl-disilazane; In dichloromethane; at -20 - 20 ℃; for 0.416667h; Yield given. Yields of byproduct given;

upstream raw materials:

poly(methacrylic acid)

1-Phenylethanol

Methacryloyl chloride

Downstream raw materials:

(S)-α-methylbenzyl methacrylate

(R)-α-methylbenzyl methacrylate