4H-1-Benzopyran-2-carboxylic acid, 7-hydroxy-8-nitro-4-oxo-, ethyl est er

Base Information

Chemical Name:4H-1-Benzopyran-2-carboxylic acid, 7-hydroxy-8-nitro-4-oxo-, ethyl est er
CAS No.:30192-14-4
Molecular Formula:C12H9 N O7
Molecular Weight:279.206
Hs Code.:
Mol file:30192-14-4.mol

Synonyms:Ethyl7-hydroxy-8-nitro-4-oxochromene-2-carboxylate

Suppliers and Price of 4H-1-Benzopyran-2-carboxylic acid, 7-hydroxy-8-nitro-4-oxo-, ethyl est er

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of 4H-1-Benzopyran-2-carboxylic acid, 7-hydroxy-8-nitro-4-oxo-, ethyl est er

Chemical Property:

PSA：122.56000
LogP:2.10670

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4H-1-Benzopyran-2-carboxylic acid, 7-hydroxy-8-nitro-4-oxo-, ethyl est er

There total 1 articles about 4H-1-Benzopyran-2-carboxylic acid, 7-hydroxy-8-nitro-4-oxo-, ethyl est er which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 30192-14-4
7-hydroxy-8-nitro-4-oxo-4H-chromene-2-carboxylic acid ethyl ester

Guidance literature:: Ester (3), HNO3;
DOI:10.1039/j39700002609

Reference yield: 94.0%

: 30192-14-4
7-hydroxy-8-nitro-4-oxo-4H-chromene-2-carboxylic acid ethyl ester

: 98-59-9
p-toluenesulfonyl chloride

: 440635-71-2
8-nitro-4-oxo-7-(toluene-4-sulfonyloxy)-4H-chromene-2-carboxylic acid ethyl ester

Guidance literature:: With potassium carbonate; In tetrahydrofuran; at 20 ℃;
DOI:10.1016/S0960-894X(01)00778-8

Reference yield:

: 30192-14-4
7-hydroxy-8-nitro-4-oxo-4H-chromene-2-carboxylic acid ethyl ester

: 8-(benzylamino-methyl)-3,6,7,8-tetrahydro-1H-chromeno[7,8-d]imidazol-2-one

Guidance literature:: Multi-step reaction with 7 steps

1: 94 percent / K₂CO₃ / tetrahydrofuran / 20 °C

2: 67 percent / 1,2-dichloro-benzene / 1 h / 170 °C

3: 97 percent / 12N HCl / 10 percent Pd/C / ethanol / 12 h

4: 86 percent / LiBH₄ / tetrahydrofuran

5: 63 percent / tetrahydrofuran / 20 °C

6: 83 percent / pyridine

7: 65 percent / dimethylsulfoxide / 80 °C

With pyridine; hydrogenchloride; lithium borohydride; potassium carbonate; palladium on activated charcoal; In tetrahydrofuran; ethanol; dimethyl sulfoxide; 1,2-dichloro-benzene;
DOI:10.1016/S0960-894X(01)00778-8