2-nitro-2'-methyl diphenyl ether carboxylate

Base Information

• Chemical Name: 2-nitro-2'-methyl diphenyl ether carboxylate
• CAS No.: 92164-06-2
• Molecular Formula: C₁₄H₁₁NO₅
• Molecular Weight: 273.245
• Mol file: 92164-06-2.mol

Synonyms:2-nitro-2'-methyl diphenyl ether carboxylate

Chemical Property of 2-nitro-2'-methyl diphenyl ether carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-nitro-2'-methyl diphenyl ether carboxylate

There total 5 articles about 2-nitro-2'-methyl diphenyl ether carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

ortho-nitrofluorobenzene (1493-27-2,127723-77-7) + methyl salicylate (119-36-8,8024-54-2) → 2-nitro-2'-methyl diphenyl ether carboxylate (92164-06-2)

Guidance literature:

With potassium carbonate; for 10h; Heating;

DOI:10.1515/HC.2007.13.2-3.165

Reference yield:

2-Chloronitrobenzene (88-73-3) + methyl salicylate (119-36-8,8024-54-2) → 2-nitro-2'-methyl diphenyl ether carboxylate (92164-06-2)

Guidance literature:

With potassium carbonate; In N-methyl-acetamide;

Reference yield:

1-methyl-2-(2-nitrophenoxy)benzene (54106-40-0) → 2-nitro-2'-methyl diphenyl ether carboxylate (92164-06-2)

Guidance literature:

Multi-step reaction with 2 steps

1: KMnO₄; aqueous pyridine

2: H₂SO₄

With pyridine; potassium permanganate; sulfuric acid;

upstream raw materials:

methanol

2-carboxy-2'-nitrodiphenyl ether

ortho-nitrofluorobenzene

methyl salicylate

Downstream raw materials:

11-chloro-dibenz<1,4>oxazepine

Refernces

• 1、 Bunce, Richard A.,Schammerhorn, James E.. "Dibenzo-fused seven-membered nitrogen heterocycles by a tandem reduction-lactamization reaction". . p. 1031 - 1035. Retrieved 2007/10/03.
• 2、 -. "Anti-inflammatory compounds". . . Retrieved 2008/06/13.