toluene-4-sulfonic acid (S)-5-fluoromethyl-7-oxo-2,3-dihydro-7H-oxazolo[3,2-a]pyrimidin-2-ylmethyl ester

Base Information

Chemical Name:toluene-4-sulfonic acid (S)-5-fluoromethyl-7-oxo-2,3-dihydro-7H-oxazolo[3,2-a]pyrimidin-2-ylmethyl ester
CAS No.:1279015-48-3
Molecular Formula:C₁₅H₁₅FN₂O₅S
Molecular Weight:354.359
Hs Code.:

Synonyms:toluene-4-sulfonic acid (S)-5-fluoromethyl-7-oxo-2,3-dihydro-7H-oxazolo[3,2-a]pyrimidin-2-ylmethyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of toluene-4-sulfonic acid (S)-5-fluoromethyl-7-oxo-2,3-dihydro-7H-oxazolo[3,2-a]pyrimidin-2-ylmethyl ester

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Technology Process of toluene-4-sulfonic acid (S)-5-fluoromethyl-7-oxo-2,3-dihydro-7H-oxazolo[3,2-a]pyrimidin-2-ylmethyl ester

There total 3 articles about toluene-4-sulfonic acid (S)-5-fluoromethyl-7-oxo-2,3-dihydro-7H-oxazolo[3,2-a]pyrimidin-2-ylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

: 1058159-93-5
toluene-4-sulfonic acid (S)-2-amino-4,5-dihydro-oxazolo-5-ylmethyl ester

: 76480-93-8
ethyl 4-fluorobut-2-ynoate

: 1279015-48-3
toluene-4-sulfonic acid (S)-5-fluoromethyl-7-oxo-2,3-dihydro-7H-oxazolo[3,2-a]pyrimidin-2-ylmethyl ester

Guidance literature:: In ethanol; for 4h; Reflux;

Reference yield:

: 70987-78-9,6746-81-2
(S)-Glycidyl tosylate

: 1279015-48-3
toluene-4-sulfonic acid (S)-5-fluoromethyl-7-oxo-2,3-dihydro-7H-oxazolo[3,2-a]pyrimidin-2-ylmethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: methanol / 18.5 h / 20 °C

2: ethanol / 4 h / Reflux

With methanol; In ethanol;