Chemical Property of (2S)-(+)-Glycidyl tosylate
Chemical Property:
- Appearance/Colour:white to light yellow crystal powder
- Melting Point:45-48 °C
- Refractive Index:1.5400 (estimate)
- Boiling Point:370.5 °C at 760 mmHg
- Flash Point:177.9 °C
- PSA:64.28000
- Density:1.31 g/cm3
- LogP:2.17990
- Storage Temp.:2-8°C
- Solubility.:Dioxane (Slightly), DMSO (Slightly), Methanol (Slightly)
- Water Solubility.:decomposes
- XLogP3:1.1
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:4
- Rotatable Bond Count:4
- Exact Mass:228.04563003
- Heavy Atom Count:15
- Complexity:298
- Purity/Quality:
-
99%, *data from raw suppliers
(2S)-(+)-Glycidyl tosylate
*data from reagent suppliers
Safty Information:
- Pictogram(s):
T,
N,
Xi
- Hazard Codes:T,N,Xi
- Statements:
45-41-43-51/53-68
- Safety Statements:
53-45-61
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)OCC2CO2
- Isomeric SMILES:CC1=CC=C(C=C1)S(=O)(=O)OC[C@@H]2CO2
-
Uses
(2S)-(+)-Glycidyl tosylate is protected Glycidol, used as an intermediate in the preparation of neurochemicals. Used in the first enantioselective synthesis of (R)- and (S)-4-acetyl-3-(hydroxymethyl)-3,4-dihydro-2H-pyrido[3,2-b]oxazines.