Technology Process of (S,11Z,19E)-3-acetoxy-11,19-octacosadien-1ol PMB ether
There total 14 articles about (S,11Z,19E)-3-acetoxy-11,19-octacosadien-1ol PMB ether which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: n-butyllithium / tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane / -65 - -10 °C / Inert atmosphere
1.2: -65 - 20 °C / Inert atmosphere; Reflux
2.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 20 °C
3.1: quinoline; hydrogen / cyclohexane / 3 h / 20 °C / 760.05 Torr
4.1: pyridine; dmap / 20 °C
With
pyridine; quinoline; dmap; n-butyllithium; tetrabutyl ammonium fluoride; hydrogen;
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane; cyclohexane;
DOI:10.1016/j.tet.2012.03.002
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: magnesium; copper(I) bromide / tetrahydrofuran
2.1: methanol; potassium carbonate
3.1: 1H-imidazole / N,N-dimethyl-formamide / 3 h / 20 °C
4.1: n-butyllithium / tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane / -65 - -10 °C / Inert atmosphere
4.2: -65 - 20 °C / Inert atmosphere; Reflux
5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 20 °C
6.1: quinoline; hydrogen / cyclohexane / 3 h / 20 °C / 760.05 Torr
7.1: pyridine; dmap / 20 °C
With
pyridine; 1H-imidazole; quinoline; methanol; dmap; n-butyllithium; tetrabutyl ammonium fluoride; hydrogen; potassium carbonate; magnesium; copper(I) bromide;
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane; cyclohexane; N,N-dimethyl-formamide;
DOI:10.1016/j.tet.2012.03.002
