Technology Process of (S,11Z,19E)-11,19-octacosadiene-1,3-diol PMB ether
There total 14 articles about (S,11Z,19E)-11,19-octacosadiene-1,3-diol PMB ether which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
quinoline; hydrogen;
In
cyclohexane;
at 20 ℃;
for 3h;
under 760.051 Torr;
stereoselective reaction;
DOI:10.1016/j.tet.2012.03.002
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: n-butyllithium / tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane / -65 - -10 °C / Inert atmosphere
1.2: -65 - 20 °C / Inert atmosphere; Reflux
2.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 20 °C
3.1: quinoline; hydrogen / cyclohexane / 3 h / 20 °C / 760.05 Torr
With
quinoline; n-butyllithium; tetrabutyl ammonium fluoride; hydrogen;
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane; cyclohexane;
DOI:10.1016/j.tet.2012.03.002
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: lithium aluminium tetrahydride / tetrahydrofuran; diethylene glycol dimethyl ether / 10 - 140 °C / Inert atmosphere
1.2: Cooling with ice
2.1: pyridine / 4 h / 0 - 5 °C
3.1: sodium iodide / N,N-dimethyl-formamide / 5 h / 80 °C
4.1: n-butyllithium / tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane / -65 - -10 °C / Inert atmosphere
4.2: -65 - 20 °C / Inert atmosphere; Reflux
5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 20 °C
6.1: quinoline; hydrogen / cyclohexane / 3 h / 20 °C / 760.05 Torr
With
pyridine; quinoline; lithium aluminium tetrahydride; n-butyllithium; tetrabutyl ammonium fluoride; hydrogen; sodium iodide;
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane; diethylene glycol dimethyl ether; cyclohexane; N,N-dimethyl-formamide;
DOI:10.1016/j.tet.2012.03.002
