3-(TRIFLUOROMETHYL)PHENYLGLYOXAL HYDRATE

Base Information

• Chemical Name: 3-(TRIFLUOROMETHYL)PHENYLGLYOXAL HYDRATE
• CAS No.: 38923-38-5
• Molecular Formula: C9H5 F3 O2
• Molecular Weight: 202.133
• Hs Code.: 2914700090
• Mol file: 38923-38-5.mol

Synonyms:3-(Trifluoromethyl)phenylglyoxal

Chemical Property of 3-(TRIFLUOROMETHYL)PHENYLGLYOXAL HYDRATE

Chemical Property:

• Vapor Pressure: 0.108mmHg at 25°C
• Boiling Point: 221.3°Cat760mmHg
• Flash Point: 83.3°C
• PSA: 34.14000
• Density: g/cm³
• LogP: 2.08700
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

3-(Trifluoromethyl)phenylglyoxal hydrate ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: R36/37/38:Irritating to eyes, respiratory system and skin.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36:Wear suitable prot

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(TRIFLUOROMETHYL)PHENYLGLYOXAL HYDRATE

There total 3 articles about 3-(TRIFLUOROMETHYL)PHENYLGLYOXAL HYDRATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3'-(trifluoromethyl)acetophenone (349-76-8) → 2-oxo-2-(3-(trifluoromethyl)phenyl)acetaldehyde (38923-38-5)

Guidance literature:

With water; hydrogen bromide; dimethyl sulfoxide; at 20 - 70 ℃;

Reference yield:

2-bromo-1-[3-(trifluoromethyl)phenyl]ethanone (2003-10-3) → 2-oxo-2-(3-(trifluoromethyl)phenyl)acetaldehyde (38923-38-5)

Guidance literature:

With dimethyl sulfoxide;

DOI:10.1021/jm00279a029

Reference yield:

→ 2-oxo-2-(3-(trifluoromethyl)phenyl)acetaldehyde (38923-38-5)

Guidance literature:

upstream raw materials:

3'-(trifluoromethyl)acetophenone

2-bromo-1-[3-(trifluoromethyl)phenyl]ethanone

Downstream raw materials:

C₂₅H₂₀F₃N₃O

C₂₂H₂₂F₃N₃O

methyl 6-oxo-1-(3-(trifluoromethyl)phenyl)-3,4,6,11-tetrahydro-2H-pyrazino[1,2-b]isoquinoline-11-carboxylate