tert-butyl 2-[3-(2,2,2-trifluoro-1-hydroxyethyl)-4-nitrophenoxy]acetate

Base Information

• Chemical Name: tert-butyl 2-[3-(2,2,2-trifluoro-1-hydroxyethyl)-4-nitrophenoxy]acetate
• CAS No.: 1036942-91-2
• Molecular Formula: C₁₄H₁₆F₃NO₆
• Molecular Weight: 351.279

Synonyms:tert-butyl 2-[3-(2,2,2-trifluoro-1-hydroxyethyl)-4-nitrophenoxy]acetate

Chemical Property of tert-butyl 2-[3-(2,2,2-trifluoro-1-hydroxyethyl)-4-nitrophenoxy]acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl 2-[3-(2,2,2-trifluoro-1-hydroxyethyl)-4-nitrophenoxy]acetate

There total 1 articles about tert-butyl 2-[3-(2,2,2-trifluoro-1-hydroxyethyl)-4-nitrophenoxy]acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

tert-butyl 2-(3-formyl-4-nitrophenoxy)acetate (1014975-09-7) + (trifluoromethyl)trimethylsilane (81290-20-2) → tert-butyl 2-[3-(2,2,2-trifluoro-1-hydroxyethyl)-4-nitrophenoxy]acetate (1036942-91-2)

Guidance literature:

tert-butyl 2-(3-formyl-4-nitrophenoxy)acetate; (trifluoromethyl)trimethylsilane; cesium fluoride; In tetrahydrofuran; 1,2-dimethoxyethane; at 20 ℃; for 5h;

With sodium hydrogensulfite; In tetrahydrofuran; 1,2-dimethoxyethane; acetone; for 1h; Further stages.;

DOI:10.1021/ja078308e

Reference yield: 95.0%

tert-butyl 2-[3-(2,2,2-trifluoro-1-hydroxyethyl)-4-nitrophenoxy]acetate (1036942-91-2) → tert-butyl 2-[3-(2,2,2-trifluoro-1-hydroxyethyl)-4-aminophenoxy]acetate (1014975-10-0)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; at 20 ℃; for 5h; under 760.051 Torr;

DOI:10.1021/ja078308e

upstream raw materials:

tert-butyl 2-(3-formyl-4-nitrophenoxy)acetate

(trifluoromethyl)trimethylsilane

Downstream raw materials:

tert-butyl 2-[3-(2,2,2-trifluoro-1-hydroxyethyl)-4-aminophenoxy]acetate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1036942-91-2 tert-butyl 2-[3-(2,2,2-trifluoro-1-hydroxyethyl)-4-nitrophenoxy]acetate

Send

Send

Metric Ton KG G Pound L ML

Send

Send