5-(benzyloxymethyl)-7-bromo-4-methoxy-5H-pyrrolo[3,2-d]pyrimidine

Base Information

Chemical Name:5-(benzyloxymethyl)-7-bromo-4-methoxy-5H-pyrrolo[3,2-d]pyrimidine
CAS No.:299916-62-4
Molecular Formula:C15H14 Br N3 O2
Molecular Weight:348.199
Hs Code.:
Nikkaji Number:J1.599.220D
Mol file:299916-62-4.mol

Synonyms:299916-62-4;5-(benzyloxymethyl)-7-bromo-4-methoxy-5H-pyrrolo[3,2-d]pyrimidine;5-((Benzyloxy)methyl)-7-bromo-4-methoxy-5H-pyrrolo[3,2-d]pyrimidine;5-[(Benzyloxy)methyl]-7-bromo-4-methoxy-5H-pyrrolo[3,2-d]pyrimidine;7-bromo-4-methoxy-5-[(phenylmethoxy)methyl]-5h-pyrrolo[3,2-d]pyrimidine;MFCD26402240;7-bromo-4-methoxy-5-(phenylmethoxymethyl)pyrrolo[3,2-d]pyrimidine;5H-Pyrrolo3,2-dpyrimidine, 7-bromo-4-methoxy-5-(phenylmethoxy)methyl-;SCHEMBL4062495;CS-M3334;ZLA91662;AKOS027324684;SB18025;AS-47060;SY244192;FT-0741427;F11817;A912767

Suppliers and Price of 5-(benzyloxymethyl)-7-bromo-4-methoxy-5H-pyrrolo[3,2-d]pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
5-((Benzyloxy)methyl)-7-bromo-4-methoxy-5H-pyrrolo[3,2-d]pyrimidine 95+%
1g
$ 748.00

Chemenu
5-((benzyloxy)methyl)-7-bromo-4-methoxy-5H-pyrrolo[3,2-d]pyrimidine 95%+
1g
$ 1550.00

Chemenu
5-((benzyloxy)methyl)-7-bromo-4-methoxy-5H-pyrrolo[3,2-d]pyrimidine 95%+
250mg
$ 496.00

Chemenu
5-((benzyloxy)methyl)-7-bromo-4-methoxy-5H-pyrrolo[3,2-d]pyrimidine 95%+
100mg
$ 403.00

Total 17 raw suppliers

Chemical Property of 5-(benzyloxymethyl)-7-bromo-4-methoxy-5H-pyrrolo[3,2-d]pyrimidine

Chemical Property:

Melting Point:98-99℃
Boiling Point:476.6±45.0 °C(Predicted)
PKA:3.65±0.40(Predicted)
PSA：49.17000
Density:1.49±0.1 g/cm3(Predicted)
LogP:3.37670
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:347.02694
Heavy Atom Count:21
Complexity:328

Purity/Quality:

97% ^*data from raw suppliers

5-((Benzyloxy)methyl)-7-bromo-4-methoxy-5H-pyrrolo[3,2-d]pyrimidine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=NC=NC2=C1N(C=C2Br)COCC3=CC=CC=C3

Technology Process of 5-(benzyloxymethyl)-7-bromo-4-methoxy-5H-pyrrolo[3,2-d]pyrimidine

There total 7 articles about 5-(benzyloxymethyl)-7-bromo-4-methoxy-5H-pyrrolo[3,2-d]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 1026012-16-7
5-(benzyloxymethyl)-4-methoxy-5H-pyrrolo[3,2-d]pyrimidine

: 299916-62-4
7-N-benzyloxymethyl-9-bromo-9-deaza-6-O-methylhypoxanthine

Guidance literature:: With N-Bromosuccinimide; In dichloromethane; at 0 - 20 ℃; for 0.5h; Inert atmosphere; Heating;

Reference yield:

: 5655-01-6
9-deazahypoxanthine

: 299916-62-4
7-N-benzyloxymethyl-9-bromo-9-deaza-6-O-methylhypoxanthine

Guidance literature:: Multi-step reaction with 4 steps

1: POCl₃

2: NaH / tetrahydrofuran / 1 h / 20 °C

3: NaH / tetrahydrofuran / 1 h

4: 6.83 g / NBS / methanol; tetrahydrofuran

With N-Bromosuccinimide; sodium hydride; trichlorophosphate; In tetrahydrofuran; methanol;
DOI:10.1021/jo0155613

Reference yield:

: 84905-80-6
4-Chloro-5H-pyrrolo[3,2-d]pyrimidine

: 299916-62-4
7-N-benzyloxymethyl-9-bromo-9-deaza-6-O-methylhypoxanthine

Guidance literature:: Multi-step reaction with 3 steps

1: NaH / tetrahydrofuran / 1 h / 20 °C

2: NaH / tetrahydrofuran / 1 h

3: 6.83 g / NBS / methanol; tetrahydrofuran

With N-Bromosuccinimide; sodium hydride; In tetrahydrofuran; methanol;
DOI:10.1021/jo0155613