dimethyl 4-carboxy-3,5-dihydroxyhomophthalate

Base Information

• Chemical Name: dimethyl 4-carboxy-3,5-dihydroxyhomophthalate
• CAS No.: 6121-79-5
• Molecular Formula: C₁₂H₁₂O₈
• Molecular Weight: 284.222
• Mol file: 6121-79-5.mol

Synonyms:dimethyl 4-carboxy-3,5-dihydroxyhomophthalate

Chemical Property of dimethyl 4-carboxy-3,5-dihydroxyhomophthalate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dimethyl 4-carboxy-3,5-dihydroxyhomophthalate

There total 3 articles about dimethyl 4-carboxy-3,5-dihydroxyhomophthalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dimethyl 2,4-dihydroxy-6-(2-methoxy-2-oxoethyl)benzene-1,3-dicarboxylate (6512-25-0) → dimethyl 4-carboxy-3,5-dihydroxyhomophthalate (6121-79-5)

Guidance literature:

With lithium chloride; In water; dimethyl sulfoxide; at 130 ℃; for 1.5h; Yield given;

DOI:10.1021/jo00375a012

Reference yield:

3-oxopentanedioic acid dimethyl ester (1830-54-2) → dimethyl 4-carboxy-3,5-dihydroxyhomophthalate (6121-79-5) + dimethyl 2,4-dihydroxy-6-(2-methoxy-2-oxoethyl)benzene-1,3-dicarboxylate (6512-25-0)

Guidance literature:

With sodium;

DOI:10.1021/jo01359a621

Reference yield:

→ dimethyl 4-carboxy-3,5-dihydroxyhomophthalate (6121-79-5)

Guidance literature:

β-Oxo-glutarsaeuredimethylester (II), 1. Na, 2. H2O, HCl;

upstream raw materials:

3-oxopentanedioic acid dimethyl ester

dimethyl 2,4-dihydroxy-6-(2-methoxy-2-oxoethyl)benzene-1,3-dicarboxylate

Downstream raw materials:

methyl <3,5-dihydroxy-2-(methoxycarbonyl)phenyl>acetate

(S)-benzyl 6,8-Bis(benzyloxy)-1-oxo-3-pentylisochroman-7-carboxylate

C₆₀H₇₀O₈Si

1-benzyl 3-methyl 2,6-bis(benzyloxy)-4-(2-methoxy-2-oxoethyl)isophthalate

Refernces