Phenyl-acetic acid 2'-hydroxy-[1,1']bi[dibenzofuranyl]-2-yl ester

Base Information

• Chemical Name: Phenyl-acetic acid 2'-hydroxy-[1,1']bi[dibenzofuranyl]-2-yl ester
• CAS No.: 190522-60-2
• Molecular Formula: C₃₂H₂₀O₅
• Molecular Weight: 484.508
• Mol file: 190522-60-2.mol

Synonyms:Phenyl-acetic acid 2'-hydroxy-[1,1']bi[dibenzofuranyl]-2-yl ester

Chemical Property of Phenyl-acetic acid 2'-hydroxy-[1,1']bi[dibenzofuranyl]-2-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of Phenyl-acetic acid 2'-hydroxy-[1,1']bi[dibenzofuranyl]-2-yl ester

There total 3 articles about Phenyl-acetic acid 2'-hydroxy-[1,1']bi[dibenzofuranyl]-2-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

phenylacetyl chloride (103-80-0) + 2,2'-dihydroxy-1,1'-bisdibenzofuranyl (190595-12-1,190595-13-2,51079-07-3) → Phenyl-acetic acid 2'-hydroxy-[1,1']bi[dibenzofuranyl]-2-yl ester (190522-60-2)

Guidance literature:

With dmap; triethylamine; In tetrahydrofuran; at -5 ℃; for 0.2h;

DOI:10.1016/S0040-4020(97)00250-0

Reference yield:

C24H12ClO5P (190522-59-9) → Phenyl-acetic acid 2'-hydroxy-[1,1']bi[dibenzofuranyl]-2-yl ester (190522-60-2)

Guidance literature:

Multi-step reaction with 3 steps

1: Et₃N / CH₂Cl₂ / 42 h / Ambient temperature

2: 88 percent / LiAlH₄ / tetrahydrofuran / 21 h / Ambient temperature

3: 84 percent / Et₃N, DMAP / tetrahydrofuran / 0.2 h / -5 °C

With dmap; lithium aluminium tetrahydride; triethylamine; In tetrahydrofuran; dichloromethane;

DOI:10.1016/S0040-4020(97)00250-0

Reference yield:

(1,1')-bi(dibenzofuranyl)-2,2'-diyl-N-(α-(S)-methylbenzyl)phosphoramidate → Phenyl-acetic acid 2'-hydroxy-[1,1']bi[dibenzofuranyl]-2-yl ester (190522-60-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 88 percent / LiAlH₄ / tetrahydrofuran / 21 h / Ambient temperature

2: 84 percent / Et₃N, DMAP / tetrahydrofuran / 0.2 h / -5 °C

With dmap; lithium aluminium tetrahydride; triethylamine; In tetrahydrofuran;

DOI:10.1016/S0040-4020(97)00250-0

upstream raw materials:

phenylacetyl chloride

2,2'-dihydroxy-1,1'-bisdibenzofuranyl

C₂₄H₁₂ClO₅P