2-(3,4-dimethoxyphenyl)-2-isopropyl-5-valeronitrile

Base Information

Chemical Name:2-(3,4-dimethoxyphenyl)-2-isopropyl-5-valeronitrile
CAS No.:124562-86-3
Molecular Formula:C₂₅H₃₃N₃O₄
Molecular Weight:439.555
Hs Code.:

2-(3,4-dimethoxyphenyl)-2-isopropyl-5-<N-(4-nitrophenethyl)methylamino>valeronitrile

Synonyms:2-(3,4-dimethoxyphenyl)-2-isopropyl-5-valeronitrile

Suppliers and Price of 2-(3,4-dimethoxyphenyl)-2-isopropyl-5-valeronitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(3,4-dimethoxyphenyl)-2-isopropyl-5-valeronitrile

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(3,4-dimethoxyphenyl)-2-isopropyl-5-valeronitrile

There total 4 articles about 2-(3,4-dimethoxyphenyl)-2-isopropyl-5-valeronitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 85176-37-0
N-methyl-N-[2-(4-nitro-phenyl)-ethyl]-amine

: 123283-25-0
2-(3,4-dimethoxyphenyl)-2-isopropyl-5-(methanesulfonoxy)valeronitrile

: 124562-86-3
2-(3,4-dimethoxyphenyl)-2-isopropyl-5-valeronitrile

Guidance literature:: With triethylamine; In 1,2-dimethoxyethane; for 16h; Heating;
DOI:10.1021/jm00164a064

Reference yield:

: 24954-63-0
2,2,2-Trifluoro-N-(2-(4-nitrophenyl)ethyl)acetamide

: 124562-86-3
2-(3,4-dimethoxyphenyl)-2-isopropyl-5-valeronitrile

Guidance literature:: Multi-step reaction with 3 steps

1: NaH / tetrahydrofuran / 2 h / Ambient temperature

2: 70 percent / aq. 5 N NaOH / methanol / 0.5 h / Ambient temperature

3: 76 percent / Et₃N / 1,2-dimethoxy-ethane / 16 h / Heating

With sodium hydroxide; sodium hydride; triethylamine; In tetrahydrofuran; methanol; 1,2-dimethoxyethane;
DOI:10.1021/jm00164a064

Reference yield:

: 124562-85-2
N-methyl-N-(2-(4-nitrophenyl)ethyl)trifluoroacetamide

: 124562-86-3
2-(3,4-dimethoxyphenyl)-2-isopropyl-5-valeronitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / aq. 5 N NaOH / methanol / 0.5 h / Ambient temperature

2: 76 percent / Et₃N / 1,2-dimethoxy-ethane / 16 h / Heating

With sodium hydroxide; triethylamine; In methanol; 1,2-dimethoxyethane;
DOI:10.1021/jm00164a064