BenzeneethanaMine, N-Methyl-4-nitro-

Base Information

• Chemical Name: BenzeneethanaMine, N-Methyl-4-nitro-
• CAS No.: 85176-37-0
• Molecular Formula: C₉H₁₂N₂O₂
• Molecular Weight: 180.206
• Mol file: 85176-37-0.mol

Synonyms:N-methyl-N-[2-(4-nitro-phenyl)-ethyl]-amine

Chemical Property of BenzeneethanaMine, N-Methyl-4-nitro-

Chemical Property:

• Boiling Point: 125-129 °C(Press: 1 Torr)
• PKA: 9.98±0.10(Predicted)
• Density: 1.130±0.06 g/cm3(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

N-Methyl-[2-(4-nitro-phenyl)-ethyl]-amine 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BenzeneethanaMine, N-Methyl-4-nitro-

There total 8 articles about BenzeneethanaMine, N-Methyl-4-nitro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

N-methyl-2-(4-nitrophenyl)acetamide (98245-61-5) → N-methyl-N-[2-(4-nitro-phenyl)-ethyl]-amine (85176-37-0)

Guidance literature:

N-methyl-2-(4-nitrophenyl)acetamide; With dimethylsulfide borane complex; In tetrahydrofuran; at 0 ℃; for 16h; Reflux;

With water; In tetrahydrofuran; Cooling with ice;

Reference yield: 70.0%

N-methyl-N-(2-(4-nitrophenyl)ethyl)trifluoroacetamide (124562-85-2) → N-methyl-N-[2-(4-nitro-phenyl)-ethyl]-amine (85176-37-0)

Guidance literature:

With sodium hydroxide; In methanol; for 0.5h; Ambient temperature;

DOI:10.1021/jm00164a064

Reference yield:

methyltertbutyl ether (67000-01-5) + 2-(4-nitrophenyl)ethylamine monohydrochloride (29968-78-3) + trifluoroacetic anhydride (407-25-0) + methyl iodide (74-88-4) → N-methyl-N-[2-(4-nitro-phenyl)-ethyl]-amine (85176-37-0)

Guidance literature:

With hydrogenchloride; sodium hydroxide; ammonia; triethylamine; In tetrahydrofuran; methanol; dichloromethane; water;

upstream raw materials:

N-methyl-N-(2-(4-nitrophenyl)ethyl)trifluoroacetamide

nitric acid

N-Methyl-N-phenethylamine

methyl-phenethyl-amine; picrate

Downstream raw materials:

4-(dimethylaminomethyl)aniline

Methyl-[4-(4-nitro-phenoxy)-butyl]-[2-(4-nitro-phenyl)-ethyl]-amine

Methyl-[2-(2-nitro-phenoxy)-ethyl]-[2-(4-nitro-phenyl)-ethyl]-amine

Methyl-[4-(4-nitro-phenyl)-butyl]-[2-(4-nitro-phenyl)-ethyl]-amine