6-O-(tert.-Butyldiphenylsilyl)-1,2,3,4-tetra-O-benzyl-β-D-glucopyranose

Base Information

Chemical Name:6-O-(tert.-Butyldiphenylsilyl)-1,2,3,4-tetra-O-benzyl-β-D-glucopyranose
CAS No.:291527-97-4
Molecular Formula:C50H54 O6 Si
Molecular Weight:779.05
Hs Code.:
Mol file:291527-97-4.mol

Synonyms:6-O-(tert.-Butyldiphenylsilyl)-1,2,3,4-tetra-O-benzyl-β-D-glucopyranose

Suppliers and Price of 6-O-(tert.-Butyldiphenylsilyl)-1,2,3,4-tetra-O-benzyl-β-D-glucopyranose

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1,2,3,4-TETRA-O-BENZYL-6-O-TERT-BUTYLDIPHENYLSILYL-BETA-D-GLUCOPYRANOSE 95.00%
5MG
$ 501.25

Total 3 raw suppliers

Chemical Property of 6-O-(tert.-Butyldiphenylsilyl)-1,2,3,4-tetra-O-benzyl-β-D-glucopyranose

Chemical Property:

PSA：55.38000
LogP:9.26090

Purity/Quality:

97% ^*data from raw suppliers

1,2,3,4-TETRA-O-BENZYL-6-O-TERT-BUTYLDIPHENYLSILYL-BETA-D-GLUCOPYRANOSE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6-O-(tert.-Butyldiphenylsilyl)-1,2,3,4-tetra-O-benzyl-β-D-glucopyranose

There total 3 articles about 6-O-(tert.-Butyldiphenylsilyl)-1,2,3,4-tetra-O-benzyl-β-D-glucopyranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 100-39-0
benzyl bromide

: 291528-10-4
benzyl 6-O-tert-butyldiphenylsilyl-β-D-glucopyranoside

: 291527-97-4
benzyl 6-O-tert-butyldiphenylsilyl-2,3,4-tri-O-benzyl-β-D-glucopyranoside

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 7h;
DOI:10.1021/jo000220v

Reference yield:

: 58479-61-1
tert-butylchlorodiphenylsilane

: 291527-97-4
benzyl 6-O-tert-butyldiphenylsilyl-2,3,4-tri-O-benzyl-β-D-glucopyranoside

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / imidazole / dimethylformamide / 3.5 h / -30 °C

2: 87 percent / NaH / dimethylformamide / 7 h / 20 °C

With 1H-imidazole; sodium hydride; In N,N-dimethyl-formamide; 1: silylation / 2: Alkylation;
DOI:10.1021/jo000220v

Reference yield:

: 4304-12-5
(2R,3R,4S,5S,6R)-2-(benzyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

: 291527-97-4
benzyl 6-O-tert-butyldiphenylsilyl-2,3,4-tri-O-benzyl-β-D-glucopyranoside

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / imidazole / dimethylformamide / 3.5 h / -30 °C

2: 87 percent / NaH / dimethylformamide / 7 h / 20 °C

With 1H-imidazole; sodium hydride; In N,N-dimethyl-formamide; 1: silylation / 2: Alkylation;
DOI:10.1021/jo000220v