tert-butyl 3-(MethylaMino)phenylcarbaMate

Base Information

• Chemical Name: tert-butyl 3-(MethylaMino)phenylcarbaMate
• CAS No.: 1134328-09-8
• Molecular Formula: C₁₂H₁₈N₂O₂
• Molecular Weight: 222.287
• Mol file: 1134328-09-8.mol

Synonyms:tert-butyl (3-(methylamino)phenyl)carbamate

Chemical Property of tert-butyl 3-(MethylaMino)phenylcarbaMate

Chemical Property:

• Boiling Point: 302.3±25.0 °C(Predicted)
• PKA: 13.62±0.70(Predicted)
• Density: 1.123±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

98%min ^*data from raw suppliers

tert-Butyl(3-(Methylamino)phenyl)carbamate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl 3-(MethylaMino)phenylcarbaMate

There total 1 articles about tert-butyl 3-(MethylaMino)phenylcarbaMate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + (3-aminophenyl)carbamic acid tert-butyl ester (68621-88-5) → tert-butyl (3-(methylamino)phenyl)carbamate (1134328-09-8)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In water; ethyl acetate; under 760.051 Torr;

Reference yield:

tert-butyl (3-(methylamino)phenyl)carbamate (1134328-09-8) + Ethanesulfonyl chloride (594-44-5) → C14H22N2O4S

Guidance literature:

With triethylamine; In acetonitrile; at 20 ℃; for 4h;

Reference yield:

4'-fluorobiphenyl-3-sulphonyl chloride (861248-58-0) + tert-butyl (3-(methylamino)phenyl)carbamate (1134328-09-8) → {3-[N-(4'-fluorobiphenyl-3-sulphonyl)-N-methylamino]phenyl}carbamic acid tert-butyl ester (1259029-80-5)

Guidance literature:

With pyridine; at 20 ℃; for 3h;

upstream raw materials:

formaldehyd

(3-aminophenyl)carbamic acid tert-butyl ester

Downstream raw materials:

{3-[N-(4'-fluorobiphenyl-3-sulphonyl)-N-methylamino]phenyl}carbamic acid tert-butyl ester

Refernces