Technology Process of 6-ETHYL-4'-HYDROXYFLAVONE
There total 6 articles about 6-ETHYL-4'-HYDROXYFLAVONE which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
palladium 10% on activated carbon; hydrogen;
In
ethyl acetate;
at 25 ℃;
for 10h;
DOI:10.1002/cmdc.201700225
- Guidance literature:
-
Multi-step reaction with 4 steps
1: aluminum (III) chloride / dichloromethane / 10 h / Cooling with ice; Reflux
2: potassium hydroxide / ethanol; water / 30 h / 20 °C
3: iodine / dimethyl sulfoxide / 2 h / 110 °C
4: hydrogen; palladium 10% on activated carbon / ethyl acetate / 10 h / 25 °C
With
aluminum (III) chloride; palladium 10% on activated carbon; hydrogen; iodine; potassium hydroxide;
In
ethanol; dichloromethane; water; dimethyl sulfoxide; ethyl acetate;
1: |Fries Phenol Ester Rearrangement / 2: |Claisen-Schmidt Condensation;
DOI:10.1002/cmdc.201700225
- Guidance literature:
-
Multi-step reaction with 5 steps
1: sulfuric acid / 0.33 h / 20 °C
2: aluminum (III) chloride / dichloromethane / 10 h / Cooling with ice; Reflux
3: potassium hydroxide / ethanol; water / 30 h / 20 °C
4: iodine / dimethyl sulfoxide / 2 h / 110 °C
5: hydrogen; palladium 10% on activated carbon / ethyl acetate / 10 h / 25 °C
With
aluminum (III) chloride; sulfuric acid; palladium 10% on activated carbon; hydrogen; iodine; potassium hydroxide;
In
ethanol; dichloromethane; water; dimethyl sulfoxide; ethyl acetate;
2: |Fries Phenol Ester Rearrangement / 3: |Claisen-Schmidt Condensation;
DOI:10.1002/cmdc.201700225
