N-((2S)-1-(benzyloxy)-4-((tert-butyldimethylsilyl)oxy)-3-methylbutan-2-yl)picolinamide

Base Information

Chemical Name:N-((2S)-1-(benzyloxy)-4-((tert-butyldimethylsilyl)oxy)-3-methylbutan-2-yl)picolinamide
CAS No.:1609204-19-4
Molecular Formula:C₂₄H₃₆N₂O₃Si
Molecular Weight:428.647
Hs Code.:

Synonyms:N-((2S)-1-(benzyloxy)-4-((tert-butyldimethylsilyl)oxy)-3-methylbutan-2-yl)picolinamide

Suppliers and Price of N-((2S)-1-(benzyloxy)-4-((tert-butyldimethylsilyl)oxy)-3-methylbutan-2-yl)picolinamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-((2S)-1-(benzyloxy)-4-((tert-butyldimethylsilyl)oxy)-3-methylbutan-2-yl)picolinamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-((2S)-1-(benzyloxy)-4-((tert-butyldimethylsilyl)oxy)-3-methylbutan-2-yl)picolinamide

There total 1 articles about N-((2S)-1-(benzyloxy)-4-((tert-butyldimethylsilyl)oxy)-3-methylbutan-2-yl)picolinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1609203-29-3
N-((2S)-1-(benzyloxy)-4-hydroxy-3-methylbutan-2-yl)picolinamide

: 18162-48-6
tert-butyldimethylsilyl chloride

: 1609204-19-4
N-((2S)-1-(benzyloxy)-4-((tert-butyldimethylsilyl)oxy)-3-methylbutan-2-yl)picolinamide

Guidance literature:: With 1H-imidazole; In N,N-dimethyl-formamide; at 10 ℃; for 0.5h;
DOI:10.1002/anie.201310000

Reference yield: 98.0%

: 1609204-19-4
N-((2S)-1-(benzyloxy)-4-((tert-butyldimethylsilyl)oxy)-3-methylbutan-2-yl)picolinamide

: 1609203-29-3
N-((2S)-1-(benzyloxy)-4-hydroxy-3-methylbutan-2-yl)picolinamide

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 10 ℃; for 0.5h;
DOI:10.1002/anie.201310000

Reference yield:

: 1609204-19-4
N-((2S)-1-(benzyloxy)-4-((tert-butyldimethylsilyl)oxy)-3-methylbutan-2-yl)picolinamide

: 1609203-28-2
(3S)-4-(benzyloxy)-2-methyl-3-(picolinamido)butyl methanesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / 10 °C

2: triethylamine / dichloromethane / 0 °C

With tetrabutyl ammonium fluoride; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1002/anie.201310000