Technology Process of (E)-((hepta-4,6-dien-2-yloxy)methyl)benzene
There total 4 articles about (E)-((hepta-4,6-dien-2-yloxy)methyl)benzene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
boron trifluoride diethyl etherate;
In
dichloromethane;
at -78 ℃;
for 13h;
optical yield given as %de;
stereoselective reaction;
Molecular sieve;
Inert atmosphere;
DOI:10.1021/jo2013466
- Guidance literature:
-
Multi-step reaction with 3 steps
1: osmium(VIII) oxide; water; 4-methylmorpholine N-oxide / tetrahydrofuran; acetonitrile / 20 °C
2: periodic acid / tetrahydrofuran / 2 h / 20 °C / Inert atmosphere
3: boron trifluoride diethyl etherate / dichloromethane / 13 h / -78 °C / Molecular sieve; Inert atmosphere
With
osmium(VIII) oxide; boron trifluoride diethyl etherate; water; 4-methylmorpholine N-oxide; periodic acid;
In
tetrahydrofuran; dichloromethane; acetonitrile;
DOI:10.1021/jo2013466
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 0 °C / Inert atmosphere
1.2: 4 h / 0 - 20 °C / Inert atmosphere
2.1: osmium(VIII) oxide; water; 4-methylmorpholine N-oxide / tetrahydrofuran; acetonitrile / 20 °C
3.1: periodic acid / tetrahydrofuran / 2 h / 20 °C / Inert atmosphere
4.1: boron trifluoride diethyl etherate / dichloromethane / 13 h / -78 °C / Molecular sieve; Inert atmosphere
With
osmium(VIII) oxide; boron trifluoride diethyl etherate; water; sodium hydride; 4-methylmorpholine N-oxide; periodic acid;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jo2013466
