dehydrogalipin

Base Information

• Chemical Name: dehydrogalipin
• CAS No.: 199279-19-1
• Molecular Formula: C₂₀H₁₉NO₃
• Molecular Weight: 321.376
• Mol file: 199279-19-1.mol

Synonyms:dehydrogalipin

Chemical Property of dehydrogalipin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dehydrogalipin

There total 10 articles about dehydrogalipin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-(2-Nitro-phenyl)-furan-2,3-dione (179243-01-7) → dehydrogalipin (199279-19-1)

Guidance literature:

Multi-step reaction with 6 steps

1: 21 percent / toluene / 1 h / 100 °C

2: 96 percent / H₂ / 10 percent Pd-C / methanol; tetrahydrofuran

3: 1.) Ba(OH)2, 2.) HCl / 1.) MeOH, H₂O, 5.5 h, heating, 2.) MeOH, H₂O

4: tetra-n-butylammonium borohydride / CH₂Cl₂ / 1 h / Ambient temperature

5: AcOH / 1 h / Heating

6: CH₂Cl₂; diethyl ether / 17 h / Ambient temperature

With hydrogenchloride; barium dihydroxide; tetra(n-butyl)ammonium borohydride; hydrogen; acetic acid; 10% palladium on active carbon; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; toluene;

DOI:10.3987/com-97-7924

Reference yield:

1,2-dimethoxy-4-<1-<(1,1-dimethylethyl)dimethylsilyloxy>ethenyl>benzene (79631-01-9) → dehydrogalipin (199279-19-1)

Guidance literature:

Multi-step reaction with 5 steps

1: 59 percent / toluene / 1 h / 100 °C

2: 45 percent / H₂ / 10 percent Pd-C / tetrahydrofuran / 5 h

3: tetra-n-butylammonium borohydride / CH₂Cl₂ / 1 h / Ambient temperature

4: AcOH / 1 h / Heating

5: CH₂Cl₂; diethyl ether / 17 h / Ambient temperature

With tetra(n-butyl)ammonium borohydride; hydrogen; acetic acid; 10% palladium on active carbon; In tetrahydrofuran; diethyl ether; dichloromethane; toluene;

DOI:10.3987/com-97-7924

Reference yield:

1-(3,4-dimethoxyphenyl)-5-(2-nitrophenyl)pentane-1,3,5-trione (199279-10-2) → dehydrogalipin (199279-19-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 45 percent / H₂ / 10 percent Pd-C / tetrahydrofuran / 5 h

2: tetra-n-butylammonium borohydride / CH₂Cl₂ / 1 h / Ambient temperature

3: AcOH / 1 h / Heating

4: CH₂Cl₂; diethyl ether / 17 h / Ambient temperature

With tetra(n-butyl)ammonium borohydride; hydrogen; acetic acid; 10% palladium on active carbon; In tetrahydrofuran; diethyl ether; dichloromethane;

DOI:10.3987/com-97-7924

upstream raw materials:

4-methoxy-2-methyl-quinoline

3,4-dimethoxy-benzaldehyde

diazomethane

1,2-dimethoxy-4-<1-<(1,1-dimethylethyl)dimethylsilyloxy>ethenyl>benzene

Downstream raw materials:

galipine