2-Hydrazino-3-nitro-5-(trifluoromethyl)pyridine

Base Information

Chemical Name:2-Hydrazino-3-nitro-5-(trifluoromethyl)pyridine
CAS No.:288246-61-7
Molecular Formula:C₆H₅F₃N₄O₂
Molecular Weight:222.127
Hs Code.:
DSSTox Substance ID:DTXSID50390887
Wikidata:Q82187996
Mol file:288246-61-7.mol

Synonyms:2-Hydrazino-3-nitro-5-(trifluoromethyl)pyridine;288246-61-7;[3-nitro-5-(trifluoromethyl)pyridin-2-yl]hydrazine;Pyridine, 2-hydrazinyl-3-nitro-5-(trifluoromethyl)-;2-hydrazinyl-3-nitro-5-(trifluoromethyl)pyridine;DTXSID50390887;AMY12237;MFCD01566807;EN300-4309216;Pyridine-2-hydrazine, 5-trifluoromethyl-3-nitro-;2-Hydrazino-3-nitro-5-(trifluoromethyl)pyridine #

Suppliers and Price of 2-Hydrazino-3-nitro-5-(trifluoromethyl)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
2-hydrazino-3-nitro-5-(trifluoromethyl)pyridine 95
10g
$ 3850.00

American Custom Chemicals Corporation
2-HYDRAZINO-3-NITRO-5-(TRIFLUOROMETHYL)PYRIDINE 95.00%
5MG
$ 502.56

AK Scientific
2-Hydrazino-3-nitro-5-(trifluoromethyl)pyridine
2.5g
$ 1683.00

Total 1 raw suppliers

Chemical Property of 2-Hydrazino-3-nitro-5-(trifluoromethyl)pyridine

Chemical Property:

PSA：96.76000
LogP:2.59070
XLogP3:1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:1
Exact Mass:222.03645990
Heavy Atom Count:15
Complexity:242

Purity/Quality:: 2-hydrazino-3-nitro-5-(trifluoromethyl)pyridine 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=NC(=C1[N+](=O)[O-])NN)C(F)(F)F

Technology Process of 2-Hydrazino-3-nitro-5-(trifluoromethyl)pyridine

There total 3 articles about 2-Hydrazino-3-nitro-5-(trifluoromethyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 72587-15-6
2-chloro-3-nitro-5-(trifluoromethyl)pyridine

: 288246-61-7
C₆H₅F₃N₄O₂

Guidance literature:: With hydrazine hydrate; In methanol; at 80 ℃; for 12h;
DOI:10.1016/j.bmcl.2013.03.119

Reference yield:

: 33252-63-0
2-hydroxy-5-(trifluoromethyl)pyridine

: 288246-61-7
C₆H₅F₃N₄O₂

Guidance literature:: Multi-step reaction with 3 steps

1: sulfuric acid; nitric acid / water / 18 h / 60 °C

2: thionyl chloride / N,N-dimethyl-formamide / 3 h / 110 °C

3: hydrazine hydrate / methanol / 12 h / 80 °C

With thionyl chloride; sulfuric acid; nitric acid; hydrazine hydrate; In methanol; water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2013.03.119

Reference yield:

: 33252-64-1
3-nitro-5-trifluoromethylpyridin-2-ol

: 288246-61-7
C₆H₅F₃N₄O₂

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / N,N-dimethyl-formamide / 3 h / 110 °C

2: hydrazine hydrate / methanol / 12 h / 80 °C

With thionyl chloride; hydrazine hydrate; In methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2013.03.119