ETHYL 2-ETHYL-4,4,4-TRIFLUORO-3-OXOBUTYRATE

Base Information Edit

Chemical Name:ETHYL 2-ETHYL-4,4,4-TRIFLUORO-3-OXOBUTYRATE
CAS No.:3854-50-0
Molecular Formula:C8H11 F3 O3
Molecular Weight:212.17
Hs Code.:2918300090
Mol file:3854-50-0.mol

Synonyms:Acetoaceticacid, 2-ethyl-4,4,4-trifluoro-, ethyl ester (7CI,8CI); Ethyl2-(trifluoroacetyl)butanoate

Suppliers and Price of ETHYL 2-ETHYL-4,4,4-TRIFLUORO-3-OXOBUTYRATE

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethyl2-ethyl-4,4,4-trifluoro-3-oxobutyrate
5g
$ 475.00

Crysdot
Ethyl2-ethyl-4,4,4-trifluoro-3-oxobutanoate 97%
5g
$ 573.00

American Custom Chemicals Corporation
ETHYL 2-ETHYL-4,4,4-TRIFLUORO-3-OXOBUTYRATE 95.00%
1G
$ 840.44

AK Scientific
Ethyl2-ethyl-4,4,4-trifluoro-3-oxobutanoate
5g
$ 1428.00

AK Scientific
Ethyl2-ethyl-4,4,4-trifluoro-3-oxobutanoate
1g
$ 433.00

Total 6 raw suppliers

Chemical Property of ETHYL 2-ETHYL-4,4,4-TRIFLUORO-3-OXOBUTYRATE Edit

Chemical Property:

Vapor Pressure:0.794mmHg at 25°C
Refractive Index:1.381
Boiling Point:95 °C
PKA:9.06±0.35(Predicted)
Flash Point:63°C
PSA：43.37000
Density:1.192g/cm³
LogP:1.70710

Purity/Quality:

95-99% ^*data from raw suppliers

Ethyl2-ethyl-4,4,4-trifluoro-3-oxobutyrate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Ethyl 2-ethyl-4,4,4-trifluoro-3-oxobutyrate is used in the synthesis of 2-?(4-?methylsulfonylphenyl) and 2-?(4-?sulfamoylphenyl)?pyrimidines which inhibit cyclooxygenase-?2 (COX-?2)?. As well Ethyl 2-ethyl-4,4,4-trifluoro-3-oxobutyrate is used in other organic reactions as a reactant.

Technology Process of ETHYL 2-ETHYL-4,4,4-TRIFLUORO-3-OXOBUTYRATE

There total 7 articles about ETHYL 2-ETHYL-4,4,4-TRIFLUORO-3-OXOBUTYRATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 407-38-5
2,2,2-trifluoroethyl trifluoroacetate

: 105-54-4
butanoic acid ethyl ester

: 3854-50-0
ethyl 2-(trifluoroacetyl)butanoate

Guidance literature:: butanoic acid ethyl ester; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 ℃; for 1h;

2,2,2-trifluoroethyl trifluoroacetate; In tetrahydrofuran; hexane; at 20 ℃;