3-amino-1-(4-nitro-phenyl)-1H-benzo[a]pyrano[2,3-c]phenazine-2-carbonitrile

Base Information

• Chemical Name: 3-amino-1-(4-nitro-phenyl)-1H-benzo[a]pyrano[2,3-c]phenazine-2-carbonitrile
• CAS No.: 1263278-19-8
• Molecular Formula: C₂₆H₁₅N₅O₃
• Molecular Weight: 445.437
• Mol file: 1263278-19-8.mol

Synonyms:3-amino-1-(4-nitro-phenyl)-1H-benzo[a]pyrano[2,3-c]phenazine-2-carbonitrile

Chemical Property of 3-amino-1-(4-nitro-phenyl)-1H-benzo[a]pyrano[2,3-c]phenazine-2-carbonitrile

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 3-amino-1-(4-nitro-phenyl)-1H-benzo[a]pyrano[2,3-c]phenazine-2-carbonitrile

There total 6 articles about 3-amino-1-(4-nitro-phenyl)-1H-benzo[a]pyrano[2,3-c]phenazine-2-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2-hydroxynaphtho-1,4-quinone (83-72-7) + 4-nitrobenzaldehdye (555-16-8) + 1,2-diamino-benzene (95-54-5) + malononitrile (109-77-3) → 3-amino-1-(4-nitro-phenyl)-1H-benzo[a]pyrano[2,3-c]phenazine-2-carbonitrile (1263278-19-8)

Guidance literature:

With Ce⁴⁺ ion immobilized on 1H-pyrazole-3,5-dicarboxylic acid modified magnetic spinel nano-CoFe₂O₄ nanocomposite; In ethanol; water; for 0.583333h; Reflux; Green chemistry;

DOI:10.1016/j.molstruc.2021.131089

Reference yield: 95.0%

1,2-benzophenazine (225-61-6) + 4-nitrobenzaldehdye (555-16-8) + malononitrile (109-77-3) → 3-amino-1-(4-nitro-phenyl)-1H-benzo[a]pyrano[2,3-c]phenazine-2-carbonitrile (1263278-19-8)

Guidance literature:

With fulvic acid; In water; at 60 ℃; for 2h; Green chemistry;

DOI:10.1080/00304948.2019.1697608

Reference yield: 79.0%

benzo[a]phenazin-5-ol (2089-82-9) + 4-nitrobenzaldehdye (555-16-8) + malononitrile (109-77-3) → 3-amino-1-(4-nitro-phenyl)-1H-benzo[a]pyrano[2,3-c]phenazine-2-carbonitrile (1263278-19-8)

Guidance literature:

With copper (II) ions-(2-amino-1H-purin-6(9H)-one) complex supported into MCM-41 mesoporous nanoparticles; for 5h; Reagent/catalyst; Green chemistry;

DOI:10.1007/s10562-020-03185-0

upstream raw materials:

2-hydroxynaphtho-1,4-quinone

benzo[a]phenazin-5-ol

4-nitrobenzaldehdye

malononitrile

Refernces

• 1、 Yazdani-Elah-Abadi, Afshin,Razeghi, Maliheh,Shams, Nasim,Kangani, Mehrnoush,Mohebat, Razieh. "Fulvic Acid: An Efficient and Green Catalyst for the One-pot Four-component Domino Synthesis of Benzo[a]phenazine Annulated Heterocycles in Aqueous Medium". . p. 48 - 55. Retrieved 2020/01/31.
• 2、 Nikoorazm, Mohsen,Khanmoradi, Maryam. "Application of Cu (II)-Guanine Complexes Anchored on SBA-15 and MCM-41 as Efficient Nanocatalysts for One-Pot, Four-Component Domino Synthesis of Phenazine Derivatives and Investigation of Their Antimicrobial Behavior". . p. 2823 - 2840. Retrieved 2020/03/30.