ethyl 2-(4-(6-chloro-2-methoxyacridin-9-ylamino)phenylamino)-2-oxoacetate

Base Information

Chemical Name:ethyl 2-(4-(6-chloro-2-methoxyacridin-9-ylamino)phenylamino)-2-oxoacetate
CAS No.:1647060-49-8
Molecular Formula:C₂₄H₂₀ClN₃O₄
Molecular Weight:449.894
Hs Code.:

Synonyms:ethyl 2-(4-(6-chloro-2-methoxyacridin-9-ylamino)phenylamino)-2-oxoacetate

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Chemical Property of ethyl 2-(4-(6-chloro-2-methoxyacridin-9-ylamino)phenylamino)-2-oxoacetate

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Technology Process of ethyl 2-(4-(6-chloro-2-methoxyacridin-9-ylamino)phenylamino)-2-oxoacetate

There total 3 articles about ethyl 2-(4-(6-chloro-2-methoxyacridin-9-ylamino)phenylamino)-2-oxoacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1203487-92-6
N-(6-chloro-2-methoxy-acridin-9-yl)-benzene-1,4-diamine

: 4755-77-5
Ethyl oxalyl chloride

: 1647060-49-8
ethyl 2-(4-(6-chloro-2-methoxyacridin-9-ylamino)phenylamino)-2-oxoacetate

Guidance literature:: With triethylamine; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1111/cbdd.12289

Reference yield:

: 86-38-4
6,9-dichloro-2-methoxyacridine

: 1647060-49-8
ethyl 2-(4-(6-chloro-2-methoxyacridin-9-ylamino)phenylamino)-2-oxoacetate

Guidance literature:: Multi-step reaction with 2 steps

1: toluene-4-sulfonic acid / ethanol / 3 h

2: triethylamine / N,N-dimethyl-formamide / 20 °C

With toluene-4-sulfonic acid; triethylamine; In ethanol; N,N-dimethyl-formamide;
DOI:10.1111/cbdd.12289

Reference yield:

: 106-50-3
1,4-phenylenediamine

: 1647060-49-8
ethyl 2-(4-(6-chloro-2-methoxyacridin-9-ylamino)phenylamino)-2-oxoacetate

Guidance literature:: Multi-step reaction with 2 steps

1: toluene-4-sulfonic acid / ethanol / 3 h

2: triethylamine / N,N-dimethyl-formamide / 20 °C

With toluene-4-sulfonic acid; triethylamine; In ethanol; N,N-dimethyl-formamide;
DOI:10.1111/cbdd.12289