N-(4-methoxyphenyl)-2-naphthylamide

Base Information

• Chemical Name: N-(4-methoxyphenyl)-2-naphthylamide
• CAS No.: 300402-61-3
• Molecular Formula: C₁₈H₁₅NO₂
• Molecular Weight: 277.323
• Mol file: 300402-61-3.mol

Synonyms:N-(4-methoxyphenyl)-2-naphthylamide

Chemical Property of N-(4-methoxyphenyl)-2-naphthylamide

Chemical Property:

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Technology Process of N-(4-methoxyphenyl)-2-naphthylamide

There total 2 articles about N-(4-methoxyphenyl)-2-naphthylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

4-methoxy-aniline (104-94-9) + naphthalene-2-carboxylate (93-09-4) → N-(4-methoxyphenyl)-2-naphthylamide (300402-61-3)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In nitromethane; Milling; Green chemistry;

DOI:10.1039/c2cc36613d

Reference yield: 84.0%

phenyl naphthalene-2-carboxylate (82408-29-5) + 4-methoxy-aniline (104-94-9) → N-(4-methoxyphenyl)-2-naphthylamide (300402-61-3)

Guidance literature:

With C₄₀H₅₄ClN₂Pd; caesium carbonate; In tetrahydrofuran; water; at 60 ℃; for 4h; Glovebox; Inert atmosphere;

DOI:10.1021/acs.joc.7b02588

upstream raw materials:

4-methoxy-aniline

naphthalene-2-carboxylate

phenyl naphthalene-2-carboxylate