3-(Diethylamino)propanamide

Base Information

• Chemical Name: 3-(Diethylamino)propanamide
• CAS No.: 3813-27-2
• Molecular Formula: C7H16 N2 O
• Molecular Weight: 144.21
• Hs Code.: 2924199090
• UNII: 75PST4XKX4
• DSSTox Substance ID: DTXSID30553751
• Nikkaji Number: J2.183.751B
• Wikidata: Q82434424
• Mol file: 3813-27-2.mol

Synonyms:3-(Diethylamino)propanamide;3813-27-2;75PST4XKX4;3-(Diethylamino)propionamide;SCHEMBL177594;DTXSID30553751;Propionamide, 3-(diethylamino)-;AKOS008962581;N~3~,N~3~-Diethyl-beta-alaninamide;CS-0370436;F87916

Chemical Property of 3-(Diethylamino)propanamide

Chemical Property:

• Vapor Pressure: 0.00871mmHg at 25°C
• Refractive Index: 1.461
• Boiling Point: 266.3°C at 760 mmHg
• PKA: 16.37±0.40(Predicted)
• Flash Point: 114.9°C
• PSA: 46.33000
• Density: 0.947g/cm³
• LogP: 0.90390
• XLogP3: -0.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 144.126263138
• Heavy Atom Count: 10
• Complexity: 99.8

Purity/Quality:

99% ^*data from raw suppliers

3-(Diethylamino)propanamide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCN(CC)CCC(=O)N

Technology Process of 3-(Diethylamino)propanamide

There total 4 articles about 3-(Diethylamino)propanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

diethylamine (109-89-7) + 2-propenamide (79-06-1,12624-24-7,25038-45-3,27754-57-0,33338-03-3,39387-77-4,68247-81-4,9082-06-8,79079-15-5) → 3-(N,N-diethylamino)propionamide (3813-27-2)

Guidance literature:

With nickel(II) ferrite; In water; at 20 ℃; Green chemistry;

DOI:10.1039/c6ra21160g

Reference yield: 59.0%

triethylamine (121-44-8) + 2-propenamide (79-06-1,12624-24-7,25038-45-3,27754-57-0,33338-03-3,39387-77-4,68247-81-4,9082-06-8,79079-15-5) → 3-(N,N-diethylamino)propionamide (3813-27-2)

Guidance literature:

With acetic acid; palladium dichloride; In tetrahydrofuran; at 70 ℃; for 48h;

DOI:10.1002/ejoc.200700369

Reference yield:

sulfuric acid mono-(2-carbamoyl-ethyl) ester (3840-67-3) + diethylamine (109-89-7) → 3-(N,N-diethylamino)propionamide (3813-27-2)

Guidance literature:

upstream raw materials:

diethylamine

2-propenamide

sulfuric acid mono-(2-carbamoyl-ethyl) ester

triethylamine