3-[(7-bromo-imidazo[1,2-a]pyridine-3-carbonyl)-amino]-4-fluoro-benzoic acid methyl ester

Base Information

Chemical Name:3-[(7-bromo-imidazo[1,2-a]pyridine-3-carbonyl)-amino]-4-fluoro-benzoic acid methyl ester
CAS No.:1426530-70-2
Molecular Formula:C₁₆H₁₁BrFN₃O₃
Molecular Weight:392.184
Hs Code.:

Synonyms:3-[(7-bromo-imidazo[1,2-a]pyridine-3-carbonyl)-amino]-4-fluoro-benzoic acid methyl ester

Suppliers and Price of 3-[(7-bromo-imidazo[1,2-a]pyridine-3-carbonyl)-amino]-4-fluoro-benzoic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
3-[(7-Bromo-imidazo[1,2-a]pyridine-3-carbonyl)-amino]-4-fluoro-benzoic acid methyl ester 95%+
1g
$ 1471.00

Advanced Chemicals Intermediatesced Chemicals Intermediates
3-[(7-Bromo-imidazo[1,2-a]pyridine-3-carbonyl)-amino]-4-fluoro-benzoicacidmethylester 95%+
1g
$ 717.75

Acints
3-[(7-Bromo-imidazo[1,2-a]pyridine-3-carbonyl)-amino]-4-fluoro-benzoicacidmethylester 95%+
5g
$ 2167.75

Acints
3-[(7-Bromo-imidazo[1,2-a]pyridine-3-carbonyl)-amino]-4-fluoro-benzoicacidmethylester 95%+
1g
$ 717.75

Total 2 raw suppliers

Chemical Property of 3-[(7-bromo-imidazo[1,2-a]pyridine-3-carbonyl)-amino]-4-fluoro-benzoic acid methyl ester

Chemical Property:

Density:1.63±0.1 g/cm3(Predicted)

Purity/Quality:

98% ^*data from raw suppliers

3-[(7-Bromo-imidazo[1,2-a]pyridine-3-carbonyl)-amino]-4-fluoro-benzoic acid methyl ester 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-[(7-bromo-imidazo[1,2-a]pyridine-3-carbonyl)-amino]-4-fluoro-benzoic acid methyl ester

There total 7 articles about 3-[(7-bromo-imidazo[1,2-a]pyridine-3-carbonyl)-amino]-4-fluoro-benzoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1019021-93-2
7-bromoimidazol[1,2-a]pyridine-3-carboxylic acid

: 369-26-6
methyl 3-amino-4-fluorobenzoate

: 1426530-70-2
3-[(7-bromo-imidazo[1,2-a]pyridine-3-carbonyl)-amino]-4-fluoro-benzoic acid methyl ester

Guidance literature:: 7-bromoimidazol[1,2-a]pyridine-3-carboxylic acid; With thionyl chloride; for 1.5h; Reflux; Inert atmosphere;

methyl 3-amino-4-fluorobenzoate; With pyridine; at 20 ℃; Inert atmosphere;

Reference yield:

: C₈H₄BrClN₂O

: 369-26-6
methyl 3-amino-4-fluorobenzoate

: 1426530-70-2
3-[(7-bromo-imidazo[1,2-a]pyridine-3-carbonyl)-amino]-4-fluoro-benzoic acid methyl ester

Guidance literature:: With pyridine; In toluene; at 20 ℃;
DOI:10.1021/acs.jmedchem.6b00703

Reference yield:

: 1134327-98-2
7-bromoimidazo[1,2-a]pyridin-3-carboxylate ethyl ester

: 1426530-70-2
3-[(7-bromo-imidazo[1,2-a]pyridine-3-carbonyl)-amino]-4-fluoro-benzoic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydroxide; water / methanol / 0.67 h / 60 °C

2.1: thionyl chloride / N,N-dimethyl acetamide / 0.5 h / 10 °C / Large scale

2.2: 0.58 h / 20 - 30 °C / Large scale

With thionyl chloride; water; sodium hydroxide; In methanol; N,N-dimethyl acetamide;