ETHYL 2,4-DIPHENYLIMIDAZOLE-5-CARBOXYLATE

Base Information

• Chemical Name: ETHYL 2,4-DIPHENYLIMIDAZOLE-5-CARBOXYLATE
• CAS No.: 37009-52-2
• Molecular Formula: C18H16 N2 O2
• Molecular Weight: 292.337
• Hs Code.: 2933290090
• Mol file: 37009-52-2.mol

Synonyms:1H-Imidazole-4-carboxylicacid, 2,5-diphenyl-, ethyl ester (9CI); Imidazole-4(or 5)-carboxylic acid,2,5(or 2,4)-diphenyl-, ethyl ester (7CI); Imidazole-4-carboxylic acid,2,5-diphenyl-, ethyl ester (6CI)

Chemical Property of ETHYL 2,4-DIPHENYLIMIDAZOLE-5-CARBOXYLATE

Chemical Property:

• PSA: 54.98000
• LogP: 3.92040

Purity/Quality:

97% ^*data from raw suppliers

ETHYL-2,4-DIPHENYLIMIDAZOLE-5-CARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ETHYL 2,4-DIPHENYLIMIDAZOLE-5-CARBOXYLATE

There total 26 articles about ETHYL 2,4-DIPHENYLIMIDAZOLE-5-CARBOXYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

ethyl 2-azido-3-phenylacrylate (61013-61-4) + benzimidic acid ethyl ester (825-60-5) → ethyl 2,4-diphenyl-1H-imidazole-5-carboxylate (37009-52-2)

Guidance literature:

In tert-butyl alcohol; at 110 ℃; Solvent; Reagent/catalyst; Time; Catalytic behavior; Sealed tube;

DOI:10.1039/c5ra07320k

Reference yield: 90.0%

N-[(ethoxycarbonyl)methyl]-N'-(thiobenzoyl)benzamidine → ethyl 2,4-diphenyl-1H-imidazole-5-carboxylate (37009-52-2)

Guidance literature:

With iodine; triethylamine; In ethyl acetate; for 1h; Ambient temperature;

DOI:10.1021/jo970072h

Reference yield: 90.0%

S-methyl thioimidate of benzoic acid (40780-81-2) + ethyl 2-azido-3-phenylacrylate (61013-61-4) → ethyl 2,4-diphenyl-1H-imidazole-5-carboxylate (37009-52-2)

Guidance literature:

In tert-butyl alcohol; at 110 ℃; for 8h; Sealed tube;

DOI:10.1039/c5ra07320k

upstream raw materials:

ethyl 2,3-dioxo-3-phenylpropanoate

benzaldehyde

glycine ethyl ester hydrochloride

3,5-diphenyl-1,2,4-dithiazol-1-ium perchlorate

Downstream raw materials:

ethyl 1-methyl-2,4-diphenyl-1H-imidazole-5-carboxylate

1-methyl-2,5-diphenyl-1H-imidazole-4-carboxylic acid ethyl ester