3-benzyloxycarbonylamino-3-methoxy-2-oxo-1-azetidinesulfonic acid, potassium salt

Base Information

• Chemical Name: 3-benzyloxycarbonylamino-3-methoxy-2-oxo-1-azetidinesulfonic acid, potassium salt
• CAS No.: 80544-02-1
• Molecular Formula: C₁₂H₁₃N₂O₇S*K
• Molecular Weight: 368.409
• Mol file: 80544-02-1.mol

Synonyms:3-benzyloxycarbonylamino-3-methoxy-2-oxo-1-azetidinesulfonic acid, potassium salt

Chemical Property of 3-benzyloxycarbonylamino-3-methoxy-2-oxo-1-azetidinesulfonic acid, potassium salt

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 3-benzyloxycarbonylamino-3-methoxy-2-oxo-1-azetidinesulfonic acid, potassium salt

There total 5 articles about 3-benzyloxycarbonylamino-3-methoxy-2-oxo-1-azetidinesulfonic acid, potassium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

potassium phosphate + 2-oxo-3-[N-chloro-N-[(phenylmethoxy)carbonyl]amino]-1-azetidinesulfonic acid, potassium salt → tetrabutylammonium salt + 3-benzyloxycarbonylamino-3-methoxy-2-oxo-1-azetidinesulfonic acid, potassium salt (80544-02-1)

Guidance literature:

With lithium methanolate; In N-methyl-acetamide; methanol; dichloromethane;

Reference yield:

benzyl N-[(3S)-2-oxoazetidin-3-yl]carbamate (80082-81-1) → 3-benzyloxycarbonylamino-3-methoxy-2-oxo-1-azetidinesulfonic acid, potassium salt (80544-02-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 98 percent / tert-butyl-hypochlorite, sodium borate / methanol / 0.5 h / 0 °C

3: trimethyl phosphite

4: 1.) pyridine-SO₃, 2.) KH₂PO₄

With sodium borate; potassium dihydrogenphosphate; tert-butylhypochlorite; sulfur trioxide pyridine complex; phosphorous acid trimethyl ester; In methanol;

DOI:10.1021/jo00340a049

Reference yield:

3-methoxy-3-[[(phenylmethoxy)carbonyl]amino]-2-azetidinone (78184-08-4) → 3-benzyloxycarbonylamino-3-methoxy-2-oxo-1-azetidinesulfonic acid, potassium salt (80544-02-1)

Guidance literature:

With potassium dihydrogenphosphate; sulfur trioxide pyridine complex; Multistep reaction;

DOI:10.1021/jo00340a049

upstream raw materials:

3-methoxy-3-[[(phenylmethoxy)carbonyl]amino]-2-azetidinone

C₁₁H₁₀Cl₂N₂O₃

(1-Chloro-3-methoxy-2-oxo-azetidin-3-yl)-carbamic acid benzyl ester

benzyl N-[(3S)-2-oxoazetidin-3-yl]carbamate