78184-08-4Relevant academic research and scientific papers
2-OXO-1-AZETIDINESULFONIC ACID SALTS
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, (2008/06/13)
Antibacterial activity is exhibited by beta-lactams having a sulfonic acid salt substituent in the 1-position and an amino or acylamino substituent in the 3-position.
Synthesis and antibacterial activity of 3-acylamino-3-methoxy-2-azetidinone-1-sulfonic acid derivatives
Matsuo,Masuya,Sugawara,Kawano,Noguchi,Ochiai
, p. 2200 - 2208 (2007/10/02)
As a key intermediate for the synthesis of sulfazecin derivatives, 3-amino-3-methoxy-2-azetidinone (24 or 26) was synthesized from penicillins, and various new compounds, including sulfazecin, were synthesized by acylation and sulfonation of 24 or 26. Som
Monobactams. The Conversion of 6-APA to (S)-3-Amino-2-oxoazetidine-1-sulfonic Acid and Its 3(RS)-Methoxy Derivative
Cimarusti, C. M.,Applegate, H. E.,Chang, H. W.,Floyd, D. M.,Koster, W. H.,et al.
, p. 179 - 180 (2007/10/02)
A facile conversion of 6-APA to (S)-3-aminomonobactamic acid (3-AMA) and its 3(RS)-methoxy derivative, key intermediates for the synthesis of 3-(acylamino)-2-oxoazetidine-1-sulfonic acids (monobactams), is described.
