(1R,2'R)-1-(1'-Boc-2'-pyrrolidinyl)-2-(o,p-dibenzyloxyphenoxy)ethyl mesylate

Base Information

Chemical Name:(1R,2'R)-1-(1'-Boc-2'-pyrrolidinyl)-2-(o,p-dibenzyloxyphenoxy)ethyl mesylate
CAS No.:1338384-80-7
Molecular Formula:C₃₂H₃₉NO₈S
Molecular Weight:597.73
Hs Code.:

Synonyms:(1R,2'R)-1-(1'-Boc-2'-pyrrolidinyl)-2-(o,p-dibenzyloxyphenoxy)ethyl mesylate

Suppliers and Price of (1R,2'R)-1-(1'-Boc-2'-pyrrolidinyl)-2-(o,p-dibenzyloxyphenoxy)ethyl mesylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1R,2'R)-1-(1'-Boc-2'-pyrrolidinyl)-2-(o,p-dibenzyloxyphenoxy)ethyl mesylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1R,2'R)-1-(1'-Boc-2'-pyrrolidinyl)-2-(o,p-dibenzyloxyphenoxy)ethyl mesylate

There total 4 articles about (1R,2'R)-1-(1'-Boc-2'-pyrrolidinyl)-2-(o,p-dibenzyloxyphenoxy)ethyl mesylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 1338384-59-0
(1R,2'R)-1-(1'-Boc-2'-pyrrolidinyl)-2-(o,p-dibenzyloxyphenoxy)ethanol

: 124-63-0
methanesulfonyl chloride

: 1338384-80-7
(1R,2'R)-1-(1'-Boc-2'-pyrrolidinyl)-2-(o,p-dibenzyloxyphenoxy)ethyl mesylate

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 5h;
DOI:10.1021/jm200937t

Reference yield:

: 152665-80-0
tert-butyl (R)-2-(2-bromoacetyl)pyrrolidine-1-carboxylate

: 1338384-80-7
(1R,2'R)-1-(1'-Boc-2'-pyrrolidinyl)-2-(o,p-dibenzyloxyphenoxy)ethyl mesylate

Guidance literature:: Multi-step reaction with 3 steps

1: acetone / 20 °C

2: sodium tetrahydroborate / tetrahydrofuran / -20 - -10 °C

3: triethylamine / dichloromethane / 5 h / 20 °C

With sodium tetrahydroborate; triethylamine; In tetrahydrofuran; dichloromethane; acetone;
DOI:10.1021/jm200937t

Reference yield:

: C₂₀H₁₇O₃^(1-)*Na⁽¹⁺⁾

: 1338384-80-7
(1R,2'R)-1-(1'-Boc-2'-pyrrolidinyl)-2-(o,p-dibenzyloxyphenoxy)ethyl mesylate

Guidance literature:: Multi-step reaction with 3 steps

1: acetone / 20 °C

2: sodium tetrahydroborate / tetrahydrofuran / -20 - -10 °C

3: triethylamine / dichloromethane / 5 h / 20 °C

With sodium tetrahydroborate; triethylamine; In tetrahydrofuran; dichloromethane; acetone;
DOI:10.1021/jm200937t