(2S,3R)-3-(4-benzyloxy-3-{(R)-1-[(S)-((S)-2-benzyloxycarbonylamino-4-methylpentyrylamino)-(tert-butoxycarbonylmethylcarbamoyl)methyl]-1-methylprop-2-ynyloxy}phenyl)-2-(tert-butoxycarbonylmethylamino)-3-hydroxypropionic acid benzyl ester

Base Information

Chemical Name:(2S,3R)-3-(4-benzyloxy-3-{(R)-1-[(S)-((S)-2-benzyloxycarbonylamino-4-methylpentyrylamino)-(tert-butoxycarbonylmethylcarbamoyl)methyl]-1-methylprop-2-ynyloxy}phenyl)-2-(tert-butoxycarbonylmethylamino)-3-hydroxypropionic acid benzyl ester
CAS No.:1013210-48-4
Molecular Formula:C₅₅H₆₈N₄O₁₃
Molecular Weight:993.164
Hs Code.:

(2S,3R)-3-(4-benzyloxy-3-{(R)-1-[(S)-((S)-2-benzyloxycarbonylamino-4-methylpentyrylamino)-(tert-butoxycarbonylmethylcarbamoyl)methyl]-1-methylprop-2-ynyloxy}phenyl)-2-(tert-butoxycarbonylmethylamino)-3-hydroxypropionic acid benzyl ester

Synonyms:(2S,3R)-3-(4-benzyloxy-3-{(R)-1-[(S)-((S)-2-benzyloxycarbonylamino-4-methylpentyrylamino)-(tert-butoxycarbonylmethylcarbamoyl)methyl]-1-methylprop-2-ynyloxy}phenyl)-2-(tert-butoxycarbonylmethylamino)-3-hydroxypropionic acid benzyl ester

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Chemical Property of (2S,3R)-3-(4-benzyloxy-3-{(R)-1-[(S)-((S)-2-benzyloxycarbonylamino-4-methylpentyrylamino)-(tert-butoxycarbonylmethylcarbamoyl)methyl]-1-methylprop-2-ynyloxy}phenyl)-2-(tert-butoxycarbonylmethylamino)-3-hydroxypropionic acid benzyl ester

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Technology Process of (2S,3R)-3-(4-benzyloxy-3-{(R)-1-[(S)-((S)-2-benzyloxycarbonylamino-4-methylpentyrylamino)-(tert-butoxycarbonylmethylcarbamoyl)methyl]-1-methylprop-2-ynyloxy}phenyl)-2-(tert-butoxycarbonylmethylamino)-3-hydroxypropionic acid benzyl ester

There total 1 articles about (2S,3R)-3-(4-benzyloxy-3-{(R)-1-[(S)-((S)-2-benzyloxycarbonylamino-4-methylpentyrylamino)-(tert-butoxycarbonylmethylcarbamoyl)methyl]-1-methylprop-2-ynyloxy}phenyl)-2-(tert-butoxycarbonylmethylamino)-3-hydroxypropionic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 870137-23-8
(2S,3R)-3-(3-{(R)-1-[(S)-amino-(tert-butoxycarbonylmethylcarbamoyl)methyl]-1-methylprop-2-ynyloxy}-4-benzyloxyphenyl)-2-(tert-butoxycarbonylmethylamino)-3-hydroxypropionic acid benzyl ester

: 2018-66-8
Z-Leu-OH

: 1013210-48-4
(2S,3R)-3-(4-benzyloxy-3-{(R)-1-[(S)-((S)-2-benzyloxycarbonylamino-4-methylpentyrylamino)-(tert-butoxycarbonylmethylcarbamoyl)methyl]-1-methylprop-2-ynyloxy}phenyl)-2-(tert-butoxycarbonylmethylamino)-3-hydroxypropionic acid benzyl ester

Guidance literature:: With sodium hydrogencarbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1021/ja710363p