(2R,3R)-5-Hydroxy-3-methyl-2-triphenylsilanyloxy-pentanoic acid ethyl ester

Base Information

Chemical Name:(2R,3R)-5-Hydroxy-3-methyl-2-triphenylsilanyloxy-pentanoic acid ethyl ester
CAS No.:500103-04-8
Molecular Formula:C₂₆H₃₀O₄Si
Molecular Weight:434.607
Hs Code.:

Synonyms:(2R,3R)-5-Hydroxy-3-methyl-2-triphenylsilanyloxy-pentanoic acid ethyl ester

Suppliers and Price of (2R,3R)-5-Hydroxy-3-methyl-2-triphenylsilanyloxy-pentanoic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,3R)-5-Hydroxy-3-methyl-2-triphenylsilanyloxy-pentanoic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,3R)-5-Hydroxy-3-methyl-2-triphenylsilanyloxy-pentanoic acid ethyl ester

There total 6 articles about (2R,3R)-5-Hydroxy-3-methyl-2-triphenylsilanyloxy-pentanoic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 76-86-8
Triphenylsilyl chloride

: 500103-04-8
(2R,3R)-5-Hydroxy-3-methyl-2-triphenylsilanyloxy-pentanoic acid ethyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 98 percent / imidazole; 4-(N,N-dimethylamino)pyridine / dimethylformamide / 0 °C

2: 95 percent / Et₃SiH / Pd/C / acetone

3: 84 percent / Zn; [(cyclopentadienyl)2ZrCl₂] / tetrahydrofuran / 0 °C

4: [(Ph₃P)3RhCl] / tetrahydrofuran / 0 °C

5: H₂O₂ / ethanol / pH 7

With 1H-imidazole; triethylsilane; dmap; Wilkinson's catalyst; zirconocene dichloride; dihydrogen peroxide; zinc; palladium on activated charcoal; In tetrahydrofuran; ethanol; N,N-dimethyl-formamide; acetone;
DOI:10.1002/1521-3773(20021202)41:23<4560::AID-ANIE4560>3.0.CO;2-B

Reference yield:

: 246510-31-6
(2R,3S)-2-Hydroxy-3-phenylsulfanylcarbonyl-butyric acid ethyl ester

: 500103-04-8
(2R,3R)-5-Hydroxy-3-methyl-2-triphenylsilanyloxy-pentanoic acid ethyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 98 percent / imidazole; 4-(N,N-dimethylamino)pyridine / dimethylformamide / 0 °C

2: 95 percent / Et₃SiH / Pd/C / acetone

3: 84 percent / Zn; [(cyclopentadienyl)2ZrCl₂] / tetrahydrofuran / 0 °C

4: [(Ph₃P)3RhCl] / tetrahydrofuran / 0 °C

5: H₂O₂ / ethanol / pH 7

With 1H-imidazole; triethylsilane; dmap; Wilkinson's catalyst; zirconocene dichloride; dihydrogen peroxide; zinc; palladium on activated charcoal; In tetrahydrofuran; ethanol; N,N-dimethyl-formamide; acetone;
DOI:10.1002/1521-3773(20021202)41:23<4560::AID-ANIE4560>3.0.CO;2-B

Reference yield:

: 500103-02-6
(2R,3S)-3-Phenylsulfanylcarbonyl-2-triphenylsilanyloxy-butyric acid ethyl ester

: 500103-04-8
(2R,3R)-5-Hydroxy-3-methyl-2-triphenylsilanyloxy-pentanoic acid ethyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 95 percent / Et₃SiH / Pd/C / acetone

2: 84 percent / Zn; [(cyclopentadienyl)2ZrCl₂] / tetrahydrofuran / 0 °C

3: [(Ph₃P)3RhCl] / tetrahydrofuran / 0 °C

4: H₂O₂ / ethanol / pH 7

With triethylsilane; Wilkinson's catalyst; zirconocene dichloride; dihydrogen peroxide; zinc; palladium on activated charcoal; In tetrahydrofuran; ethanol; acetone;
DOI:10.1002/1521-3773(20021202)41:23<4560::AID-ANIE4560>3.0.CO;2-B