TMPYP

Base Information

• Chemical Name: TMPYP
• CAS No.: 36951-72-1
• Molecular Formula: C72H66N8O12S4
• Molecular Weight: 1363.63
• Mol file: 36951-72-1.mol

Synonyms:4,4',4'',4'''-Porphyrin-5,10,15,20-tetrayltetrakis(1-methylpyridinium) tetrakis(4-methylbenzenesulfonate);4-Methylbenzenesulfonate; 5,10,15,20-tetrakis(1-methylpyridin-1-ium-4-yl)-21,22-dihydroporphyrin;

Chemical Property of TMPYP

Chemical Property:

• Melting Point: >300℃
• PSA: 334.14000
• LogP: 10.08380
• Storage Temp.: 2-8°C
• Solubility.: water: soluble50MM(lit.)

Purity/Quality:

97% ^*data from raw suppliers

TMPyP4 tosylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37

MSDS Files:

SDS file from LookChem

Useful:

• Uses: TMPyP4 is a potent inhibitor of telomerase activity.

Technology Process of TMPYP

There total 2 articles about TMPYP which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

methyl p-toluene sulfonate (80-48-8) + 5,10,15,20-tetra(4-pyridyl)-21H,23H-porphine (16834-13-2) → tetra(4-N-methylpyridyl)porphyrin tosylate (36951-72-1)

Guidance literature:

In N,N-dimethyl-formamide; for 16h; Reflux; Darkness;

DOI:10.1021/acs.inorgchem.5b00924

Reference yield:

tetra(4-N-methylpyridyl)porphyrin tosylate (36951-72-1) → C44H38N8(3+)*4C7H7O3S(1-) + C44H39N8(4+)*4C7H7O3S(1-) (36951-72-1)

Guidance literature:

With isopropyl alcohol; dinitrogen monoxide; In water; Rate constant; Product distribution; Irradiation; pH=7.0; pulse radiolysis; other reaction method, reagent and solvent;

DOI:10.1039/f19827800127

Reference yield: 84.0%

zinc diacetate (557-34-6) + tetra(4-N-methylpyridyl)porphyrin tosylate (36951-72-1) → {Zn(meso-tetrakis(1-methylpyridinium-4-yl)porphyrin)} tetratosylate

Guidance literature:

In water; for 2h; Reflux;

DOI:10.1039/c6dt04753j

upstream raw materials:

methyl p-toluene sulfonate

5,10,15,20-tetra(4-pyridyl)-21H,23H-porphine

Downstream raw materials:

5,10,15,20-tetrakis(4-methylpyridinium)porphyrin tetrahydrochloride