5-methyl-8-propionyl-9-oxo-12-benzyl-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole

Base Information

• Chemical Name: 5-methyl-8-propionyl-9-oxo-12-benzyl-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole
• CAS No.: 141804-37-7
• Molecular Formula: C₂₅H₂₆N₂O₂
• Molecular Weight: 386.494
• Mol file: 141804-37-7.mol

Synonyms:5-methyl-8-propionyl-9-oxo-12-benzyl-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole

Chemical Property of 5-methyl-8-propionyl-9-oxo-12-benzyl-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-methyl-8-propionyl-9-oxo-12-benzyl-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole

There total 3 articles about 5-methyl-8-propionyl-9-oxo-12-benzyl-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2-benzyl-3-methoxycarbonyl-1,2,3,4-tetrahydro-9-methyl-pyrido-<3,4b>indole-1-(3-pentanone) (68014-42-6,68014-43-7,141804-29-7,141816-68-4) → 5-methyl-8-propionyl-9-oxo-12-benzyl-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole (141804-37-7)

Guidance literature:

With potassium hydride; In 1,4-dioxane; for 1.5h; Heating;

DOI:10.1016/S0040-4020(01)88507-0

Reference yield:

4-oxohexanal (25346-59-2) → 5-methyl-8-propionyl-9-oxo-12-benzyl-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole (141804-37-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 93.9 percent / benzene / 8 h / Heating

2: 98 percent / KH / dioxane / 1.5 h / Heating

With potassium hydride; In 1,4-dioxane; benzene;

DOI:10.1016/S0040-4020(01)88507-0

Reference yield:

(+/-)-Na-methyl-Nb-benzyltriptophan methyl ester (19779-76-1) → 5-methyl-8-propionyl-9-oxo-12-benzyl-6,7,8,9,10,11-hexahydro-6,10-imino-5H-cyclooctindole (141804-37-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 93.9 percent / benzene / 8 h / Heating

2: 98 percent / KH / dioxane / 1.5 h / Heating

With potassium hydride; In 1,4-dioxane; benzene;

DOI:10.1016/S0040-4020(01)88507-0

upstream raw materials:

2-benzyl-3-methoxycarbonyl-1,2,3,4-tetrahydro-9-methyl-pyrido-<3,4b>indole-1-(3-pentanone)

4-oxohexanal

(+/-)-N_a-methyl-N_b-benzyltriptophan methyl ester