N-(3-isopropyl-benzylidene)-N'-(7-morpholin-4-yl-2-Pyridin-4-yl-pyrazolo[1,5-a]pyrimidin-5-yl)-hydrazine

Base Information

Chemical Name:N-(3-isopropyl-benzylidene)-N'-(7-morpholin-4-yl-2-Pyridin-4-yl-pyrazolo[1,5-a]pyrimidin-5-yl)-hydrazine
CAS No.:1232222-98-8
Molecular Formula:C₂₅H₂₇N₇O
Molecular Weight:441.536
Hs Code.:

Synonyms:N-(3-isopropyl-benzylidene)-N'-(7-morpholin-4-yl-2-Pyridin-4-yl-pyrazolo[1,5-a]pyrimidin-5-yl)-hydrazine

Suppliers and Price of N-(3-isopropyl-benzylidene)-N'-(7-morpholin-4-yl-2-Pyridin-4-yl-pyrazolo[1,5-a]pyrimidin-5-yl)-hydrazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(3-isopropyl-benzylidene)-N'-(7-morpholin-4-yl-2-Pyridin-4-yl-pyrazolo[1,5-a]pyrimidin-5-yl)-hydrazine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(3-isopropyl-benzylidene)-N'-(7-morpholin-4-yl-2-Pyridin-4-yl-pyrazolo[1,5-a]pyrimidin-5-yl)-hydrazine

There total 4 articles about N-(3-isopropyl-benzylidene)-N'-(7-morpholin-4-yl-2-Pyridin-4-yl-pyrazolo[1,5-a]pyrimidin-5-yl)-hydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 26.0%

: 1232225-20-5
(7-morpholin-4-yl-2-pyridin-4-yl-pyrazolo[1,5-a]pyrimidin-5-yl)-hydrazine

: 34246-57-6
3-isopropylbenzaldehyde

: 1232222-98-8
N-(3-isopropyl-benzylidene)-N'-(7-morpholin-4-yl-2-Pyridin-4-yl-pyrazolo[1,5-a]pyrimidin-5-yl)-hydrazine

Guidance literature:: In ethanol; at 1 - 30 ℃;

Reference yield:

: 1570-45-2
isonicotinic acid ethylester

: 1232222-98-8
N-(3-isopropyl-benzylidene)-N'-(7-morpholin-4-yl-2-Pyridin-4-yl-pyrazolo[1,5-a]pyrimidin-5-yl)-hydrazine

Guidance literature:: Multi-step reaction with 5 steps

1.1: potassium tert-butylate / 18-crown-6 ether / tetrahydrofuran / 0.08 h / 60 °C

1.2: 0.5 h

1.3: 20 h / 30 °C / Cooling with ice

2.1: sodium ethanolate / ethanol / 9 h / Reflux

2.2: 4 h / Cooling with ice; Reflux

3.1: 1,4-dioxane / 1 h / 1 - 30 °C

4.1: hydrazine hydrate / 1,4-dioxane / 10 h / Reflux

5.1: ethanol / 1 - 30 °C

With potassium tert-butylate; sodium ethanolate; hydrazine hydrate; 18-crown-6 ether; In tetrahydrofuran; 1,4-dioxane; ethanol;

Reference yield:

: 1232224-69-9
5-chloro-7-morpholin-4-yl-2-pyridin-4-yl-pyrazolo[1,5-a]pyrimidine

: 1232222-98-8
N-(3-isopropyl-benzylidene)-N'-(7-morpholin-4-yl-2-Pyridin-4-yl-pyrazolo[1,5-a]pyrimidin-5-yl)-hydrazine

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine hydrate / 1,4-dioxane / 10 h / Reflux

2: ethanol / 1 - 30 °C

With hydrazine hydrate; In 1,4-dioxane; ethanol;