Fmoc-[D]Gly-OH

Base Information

Chemical Name:Fmoc-[D]Gly-OH
CAS No.:284665-11-8
Molecular Formula:C17H13 D2 N O4
Molecular Weight:299.295
Hs Code.:
DSSTox Substance ID:DTXSID90583857
Wikidata:Q82475463
Mol file:284665-11-8.mol

Synonyms:284665-11-8;Fmoc-[D]Gly-OH;Fmoc-Gly-OH-2,2-d2;GLYCINE-2,2-D2-N-FMOC;2,2-dideuterio-2-(9H-fluoren-9-ylmethoxycarbonylamino)acetic acid;Fmoc-[D2]Gly-OH;Fmoc-[DGly-OH;Fmoc-Gly-OH-2,2 D2;SCHEMBL4656672;DTXSID90583857;HY-Y1250S2;MFCD01075436;Fmoc-Gly-OH-2,2-d2, 98 atom % D;MS-24305;CS-0226283;D99725;N-{[(9H-Fluoren-9-yl)methoxy]carbonyl}(2,2-~2~H_2_)glycine

Suppliers and Price of Fmoc-[D]Gly-OH

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-Fmoc-glycine-d2
10mg
$ 50.00

Sigma-Aldrich
Fmoc-Gly-OH-2,2-d2 98 atom % D
1g
$ 793.00

Medical Isotopes, Inc.
Glycine-2,2-d2-N-t-FMOC
0.5 g
$ 880.00

American Custom Chemicals Corporation
FMOC-GLY-OH-2,2-D2 95.00%
5MG
$ 499.16

Total 8 raw suppliers

Chemical Property of Fmoc-[D]Gly-OH

Chemical Property:

Melting Point:174-175 °C(lit.)
PSA：75.63000
LogP:3.00060
Storage Temp.:2-8°C
XLogP3:2.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:299.11266145
Heavy Atom Count:22
Complexity:403

Purity/Quality:

97% ^*data from raw suppliers

N-Fmoc-glycine-d2 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCC(=O)O
Isomeric SMILES:[2H]C([2H])(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
Uses Isotope labelled N-Fmoc-glycine is an N-Fmoc-protected form of Glycine (G615990). Glycine is a nonessential amino acid that acts as an inhibitory neyrotransmitter in the vertebrate central nervous system. Glycine also posesses cytoprotective against oxidant damage in the kidney.

Technology Process of Fmoc-[D]Gly-OH

There total 1 articles about Fmoc-[D]Gly-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4896-75-7
<2-2H2>glycine

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 284665-11-8
Fmoc-α-d2-glycine

Guidance literature:: With sodium hydrogencarbonate; In 1,4-dioxane; water;
DOI:10.1007/s13361-012-0540-6

Reference yield:

: 29022-11-5
N-(fluoren-9-ylmethoxycarbonyl)glycine

: 35661-60-0
Fmoc-Leu-OH

: 35661-39-3,136132-75-7
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine

: 284665-11-8
Fmoc-α-d2-glycine

: C₂₈H₄₃⁽²⁾H₂N₉O₈

Guidance literature:: Fmoc-α-d2-glycine; With 2,6-Dichlorobenzoyl chloride; Wang resin

With piperidine; Wang resin

N-(fluoren-9-ylmethoxycarbonyl)glycine; Fmoc-Leu-OH; N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine; Fmoc-Arg(Pg)-OH; Fmoc-Tyr(Pg)-OH; Further stages;
DOI:10.1007/s13361-012-0540-6