methyl 2-(2-chlorophenyl)-2-(2-(2,4-dichlorobenzyl)hydrazono)acetate

Base Information

• Chemical Name: methyl 2-(2-chlorophenyl)-2-(2-(2,4-dichlorobenzyl)hydrazono)acetate
• CAS No.: 1403825-55-7
• Molecular Formula: C₁₆H₁₃Cl₃N₂O₂
• Molecular Weight: 371.65
• Mol file: 1403825-55-7.mol

Synonyms:methyl 2-(2-chlorophenyl)-2-(2-(2,4-dichlorobenzyl)hydrazono)acetate

Chemical Property of methyl 2-(2-chlorophenyl)-2-(2-(2,4-dichlorobenzyl)hydrazono)acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2-(2-chlorophenyl)-2-(2-(2,4-dichlorobenzyl)hydrazono)acetate

There total 3 articles about methyl 2-(2-chlorophenyl)-2-(2-(2,4-dichlorobenzyl)hydrazono)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.4%

methyl 2-chlorobenzoylformate (34966-49-9) + (2,4-dichlorobenzyl)hydrazine dihydrochloride (1469998-19-3,879645-40-6) → methyl 2-(2-chlorophenyl)-2-(2-(2,4-dichlorobenzyl)hydrazono)acetate (1403825-55-7)

Guidance literature:

With potassium carbonate; In isopropyl alcohol; at 50 - 55 ℃; for 1h;

DOI:10.1080/00397911.2012.696306

Reference yield:

2-chlorobenzoyl cyanide (35022-42-5) → methyl 2-(2-chlorophenyl)-2-(2-(2,4-dichlorobenzyl)hydrazono)acetate (1403825-55-7)

Guidance literature:

Multi-step reaction with 3 steps

1: sulfuric acid; water

2: thionyl chloride

3: potassium carbonate / isopropyl alcohol / 1 h / 50 - 55 °C

With thionyl chloride; sulfuric acid; water; potassium carbonate; In isopropyl alcohol;

DOI:10.1080/00397911.2012.696306

Reference yield:

2-(2-chlorophenyl)-2-oxoacetamide → methyl 2-(2-chlorophenyl)-2-(2-(2,4-dichlorobenzyl)hydrazono)acetate (1403825-55-7)

Guidance literature:

Multi-step reaction with 2 steps

1: thionyl chloride

2: potassium carbonate / isopropyl alcohol / 1 h / 50 - 55 °C

With thionyl chloride; potassium carbonate; In isopropyl alcohol;

DOI:10.1080/00397911.2012.696306

upstream raw materials:

methyl 2-chlorobenzoylformate

(2,4-dichlorobenzyl)hydrazine dihydrochloride

2-chlorobenzoyl cyanide

Downstream raw materials:

methyl 1-(2,4-dichlorobenzyl)-1H-indazole-3-carboxylate

(1-(2,4-dichlorobenzyl)-1H-indazol-3-yl)methanol

1-(2,4-dichlorobenzyl)-1H-indazole-3-carbaldehyde