Technology Process of 2-(4-tolylsulfinyl)-3-(4-tolylthio)phenyl triflate
There total 5 articles about 2-(4-tolylsulfinyl)-3-(4-tolylthio)phenyl triflate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2-(p-tolylsulfinyl)phenyl triflate;
With
2,2,6,6-tetramethylpiperidinylmagnesium chloride lithium chloride complex;
In
tetrahydrofuran; toluene;
at -30 ℃;
for 0.333333h;
Inert atmosphere;
di(4-methyl)phenylthiosulfonate;
In
tetrahydrofuran; toluene;
at -30 ℃;
for 1h;
Inert atmosphere;
DOI:10.1246/cl.130899
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: n-butyllithium / diethyl ether; hexane / 2 h / -78 - 20 °C / Inert atmosphere
1.2: 12 h / -78 - 20 °C / Inert atmosphere
2.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 12 h / -78 - 20 °C / Inert atmosphere
3.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 12 h / 0 - 20 °C / Inert atmosphere
4.1: 2,2,6,6-tetramethylpiperidinylmagnesium chloride lithium chloride complex / tetrahydrofuran; toluene / 0.33 h / -30 °C / Inert atmosphere
4.2: 1 h / -30 °C / Inert atmosphere
With
n-butyllithium; 2,2,6,6-tetramethylpiperidinylmagnesium chloride lithium chloride complex; N-ethyl-N,N-diisopropylamine; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; diethyl ether; hexane; dichloromethane; toluene;
DOI:10.1246/cl.130899
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 12 h / 0 - 20 °C / Inert atmosphere
2.1: 2,2,6,6-tetramethylpiperidinylmagnesium chloride lithium chloride complex / tetrahydrofuran; toluene / 0.33 h / -30 °C / Inert atmosphere
2.2: 1 h / -30 °C / Inert atmosphere
With
2,2,6,6-tetramethylpiperidinylmagnesium chloride lithium chloride complex; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; dichloromethane; toluene;
DOI:10.1246/cl.130899
