1609119-99-4

Upstream product

• 95-56-7 2-hydroxybromobenzene 
• 59010-83-2 1-methyl-4-(2-hydroxylphenyl)thiobenzene 
• 1609120-00-4 2-(4-tolylthio)phenyl triflate 
• 2943-42-2 di(4-methyl)phenylthiosulfonate 

Downstream Products

• 1609120-05-9 1-benzyl-4-(4-tolylthio)-1,2,3-benzotriazole 
• 1609120-06-0 1-benzyl-7-(4-tolylthio)-1,2,3-benzotriazole 
• 4706-43-8 1-benzyl-1H-benzotriazole 
• 1253786-03-6 2-(tert-butyl)-2,3-dihydro-3-phenyl-1,2-benzoisoxazole 
• 19061-38-2 (9s,10s)-9,10-diphenyl-9,10-dihydro-9,10-epoxyanthracene 
• 1609120-04-8 2-(4-tolylsulfinyl)-3-(4-tolylthio)phenyl triflate 
• 84-85-5 4-methoxynaphth-1-ol 
• 751-38-2 1,2,3,4-tetraphenylnaphthalene 

Relevant academic research and scientific papers

Generation of arynes triggered by sulfoxidemetal exchange reaction of ortho-sulfinylaryl triflates

Arynes were efficiently generated from readily available ortho-sulfinylaryl triflates by the treatment with phenylmagnesium bromide in tetrahydrofuran at 78 C. Aryne generation was initiated by a rapid sulfoxidemetal exchange reaction, followed by the immediate elimination of the ortho-OTf group. Various arynophiles efficiently reacted with arynes generated by this method within 10min, providing the corresponding adducts in high yields.