5'-O-adenosine

Base Information

• Chemical Name: 5'-O-adenosine
• CAS No.: 137957-36-9
• Molecular Formula: C₂₄H₃₀N₆O₇
• Molecular Weight: 514.538

Synonyms:5'-O-adenosine

Chemical Property of 5'-O-adenosine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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Technology Process of 5'-O-adenosine

There total 3 articles about 5'-O-adenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

N-tert-butoxycarbonyl-L-phenylalanine (13734-34-4) + adenosine (58-61-7) → 5'-O-adenosine (137957-36-9)

Guidance literature:

With diethylazodicarboxylate; In N,N,N,N,N,N-hexamethylphosphoric triamide; at 20 ℃; for 24h;

Reference yield: 38.0%

Boc-Phe-ONSu (3674-06-4) + adenosine (58-61-7) → 5'-O-adenosine (137957-36-9)

Guidance literature:

In N,N-dimethyl-formamide; at 0 ℃; for 0.5h; subtilisine, sonication;

Reference yield:

Boc-Phe-ONSu (3674-06-4) + adenosine (58-61-7) → N6--adenosine (137957-37-0) + 5'-O-adenosine (137957-36-9) + bis 5'-O,N6-adenosine (137957-38-1)

Guidance literature:

In N,N-dimethyl-formamide; at 45 ℃; for 120h; Yield given. Yields of byproduct given;

upstream raw materials:

N-tert-butoxycarbonyl-L-phenylalanine

adenosine

Boc-Phe-ONSu

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