6'-O-tert-butyldimethylsilyl-4'-O-mesyl-6,3',2'',5'',3''', 4'''-hexa-O-methoxycarbonyl-per-N-Cbz-paromomycin

Base Information

Chemical Name:6'-O-tert-butyldimethylsilyl-4'-O-mesyl-6,3',2'',5'',3''', 4'''-hexa-O-methoxycarbonyl-per-N-Cbz-paromomycin
CAS No.:1284216-85-8
Molecular Formula:C₈₂H₁₀₃N₅O₃₈SSi
Molecular Weight:1826.88
Hs Code.:

Synonyms:6'-O-tert-butyldimethylsilyl-4'-O-mesyl-6,3',2'',5'',3''', 4'''-hexa-O-methoxycarbonyl-per-N-Cbz-paromomycin

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6'-O-tert-butyldimethylsilyl-4'-O-mesyl-6,3',2'',5'',3''', 4'''-hexa-O-methoxycarbonyl-per-N-Cbz-paromomycin

Chemical Property:

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Technology Process of 6'-O-tert-butyldimethylsilyl-4'-O-mesyl-6,3',2'',5'',3''', 4'''-hexa-O-methoxycarbonyl-per-N-Cbz-paromomycin

There total 1 articles about 6'-O-tert-butyldimethylsilyl-4'-O-mesyl-6,3',2'',5'',3''', 4'''-hexa-O-methoxycarbonyl-per-N-Cbz-paromomycin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1284216-84-7
6'-O-tert-butyldimethylsilyl-6,3',2'',5'',3''', 4'''-hexa-O-methoxycarbonyl-per-N-Cbz-paromomycin

: 124-63-0
methanesulfonyl chloride

: 1284216-85-8
6'-O-tert-butyldimethylsilyl-4'-O-mesyl-6,3',2'',5'',3''', 4'''-hexa-O-methoxycarbonyl-per-N-Cbz-paromomycin

Guidance literature:: 6'-O-tert-butyldimethylsilyl-6,3',2'',5'',3''', 4'''-hexa-O-methoxycarbonyl-per-N-Cbz-paromomycin; methanesulfonyl chloride; With pyridine; at 0 - 20 ℃; for 3h;

With methanol; In pyridine; for 0.5h;

Reference yield: 97.0%

: 1284216-85-8
6'-O-tert-butyldimethylsilyl-4'-O-mesyl-6,3',2'',5'',3''', 4'''-hexa-O-methoxycarbonyl-per-N-Cbz-paromomycin

: 1284216-83-6
4'-O-mesyl-6,3',2'',5'',3''', 4'''-hexa-O-methoxycarbonyl-per-N-Cbz-paromomycin

Guidance literature:: 6'-O-tert-butyldimethylsilyl-4'-O-mesyl-6,3',2'',5'',3''', 4'''-hexa-O-methoxycarbonyl-per-N-Cbz-paromomycin; With pyridine hydrofluoride; In methanol; at 0 ℃;

With water; sodium hydrogencarbonate; In methanol;