(4-Methoxy-benzyl)-phosphonic acid isopropyl ester 2-thioxo-2H-pyridin-1-yl ester

Base Information

• Chemical Name: (4-Methoxy-benzyl)-phosphonic acid isopropyl ester 2-thioxo-2H-pyridin-1-yl ester
• CAS No.: 117309-25-8
• Molecular Formula: C₁₆H₂₀NO₄PS
• Molecular Weight: 353.379
• Mol file: 117309-25-8.mol

Synonyms:(4-Methoxy-benzyl)-phosphonic acid isopropyl ester 2-thioxo-2H-pyridin-1-yl ester

Chemical Property of (4-Methoxy-benzyl)-phosphonic acid isopropyl ester 2-thioxo-2H-pyridin-1-yl ester

Chemical Property:

Purity/Quality:

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Technology Process of (4-Methoxy-benzyl)-phosphonic acid isopropyl ester 2-thioxo-2H-pyridin-1-yl ester

There total 1 articles about (4-Methoxy-benzyl)-phosphonic acid isopropyl ester 2-thioxo-2H-pyridin-1-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-hydroxy-2(1H)-pyridinethione (1121-30-8) + C11H16ClO3P → (4-Methoxy-benzyl)-phosphonic acid isopropyl ester 2-thioxo-2H-pyridin-1-yl ester (117309-25-8)

Guidance literature:

With dmap;

DOI:10.1021/ja00231a067

Reference yield: 52.0%

(4-Methoxy-benzyl)-phosphonic acid isopropyl ester 2-thioxo-2H-pyridin-1-yl ester (117309-25-8) + tert-butyl alcohol (75-65-0) → isopropyl tert-butyl phosphate + C22H32O7P2

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; Mechanism; multistep reaction; monomeric metaphosphate formation during radical-based dephosphorilation, metaphosphate interception, trapping efficiency;

DOI:10.1021/ja00231a067

Reference yield: 28.0%

(4-Methoxy-benzyl)-phosphonic acid isopropyl ester 2-thioxo-2H-pyridin-1-yl ester (117309-25-8) → p-methylanizole (104-93-8)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene; Heating;

DOI:10.1021/ja00231a067

upstream raw materials:

1-hydroxy-2(1H)-pyridinethione

Downstream raw materials:

p-methylanizole

p-methoxybenzyl chloride

Refernces