2-Phenyl-1-propylboronic acid pinacol ester, 97%

Base Information

• Chemical Name: 2-Phenyl-1-propylboronic acid pinacol ester, 97%
• CAS No.: 280559-30-0
• Molecular Formula: C15H23 B O2
• Molecular Weight: 246.157
• Hs Code.: 2934999090
• Mol file: 280559-30-0.mol

Synonyms:4,4,5,5-Tetramethyl-2-(2-phenylpropyl)-1,3,2-dioxaborolane

Chemical Property of 2-Phenyl-1-propylboronic acid pinacol ester, 97%

Chemical Property:

• Boiling Point: 298.4±19.0 °C(Predicted)
• PSA: 18.46000
• Density: 0.96±0.1 g/cm3(Predicted)
• LogP: 3.88230
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

4,4,5,5-Tetramethyl-2-(2-phenylpropyl)-1,3,2-dioxaborolane 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Phenyl-1-propylboronic acid pinacol ester, 97%

There total 25 articles about 2-Phenyl-1-propylboronic acid pinacol ester, 97% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) + isopropenylbenzene (98-83-9,6144-04-3,25014-31-7,42612-14-6) → 2-(2-phenyl-2-methylethyl)-4,4,5,5-tetramethyl-[1,3,2]-dioxaborolane (280559-30-0)

Guidance literature:

With sodium triethylborohydride; at 23 ℃; Catalytic behavior; Inert atmosphere;

Reference yield: 99.0%

bis(pinacol)diborane (73183-34-3) + isopropenylbenzene (98-83-9,6144-04-3,25014-31-7,42612-14-6) → 2-(2-phenyl-2-methylethyl)-4,4,5,5-tetramethyl-[1,3,2]-dioxaborolane (280559-30-0)

Guidance literature:

With potassium tert-butylate; iron(II) chloride; tert-butyl alcohol; In tetrahydrofuran; at 65 ℃; for 12h; Inert atmosphere; Schlenk technique; Green chemistry;

DOI:10.1039/c5ra14869c

Reference yield: 65.0%

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) + isopropenylbenzene (98-83-9,6144-04-3,25014-31-7,42612-14-6) → (R)-2,2'-(2-phenylpropane-1,1-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) + 2-(2-phenyl-2-methylethyl)-4,4,5,5-tetramethyl-[1,3,2]-dioxaborolane (280559-30-0)

Guidance literature:

With (R)-(+)-(4,4'-bi-1,3-benzodioxole)-5,5'-diylbis(di(3,5-dimethylphenyl)phosphine); cobalt acetylacetonate; 1,2-cyclooctene; In tetrahydrofuran; at 20 ℃; for 24h; Reagent/catalyst; Temperature; enantioselective reaction; Catalytic behavior; Inert atmosphere; Sealed tube;

DOI:10.1002/anie.201805705

upstream raw materials:

Isopropylbenzene

bis(pinacol)diborane

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

isopropenylbenzene

Downstream raw materials:

(RS)-2-phenyl-1-propanol

(S)-2-phenyl-1-propanol

(+)-(R)-2-phenylpropanol

ethyl 2-methylene-5-phenylhexanoate