Benzenesulfonamide, 2-hydroxy- (9CI)

Base Information

• Chemical Name: Benzenesulfonamide, 2-hydroxy- (9CI)
• CAS No.: 3724-14-9
• Molecular Formula: C6H7 N O3 S
• Molecular Weight: 173.192
• Hs Code.: 2935009090
• Mol file: 3724-14-9.mol

Synonyms:1-Phenol-2-sulfonamide(6CI); Benzenesulfonamide, o-hydroxy- (7CI,8CI); 2-Hydroxybenzenesulfonamide;2-Hydroxyphenylsulfonamide

Chemical Property of Benzenesulfonamide, 2-hydroxy- (9CI)

Chemical Property:

• PSA: 88.77000
• LogP: 1.82070

Purity/Quality:

98%min ^*data from raw suppliers

2-hydroxybenzene-1-sulfonamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenesulfonamide, 2-hydroxy- (9CI)

There total 12 articles about Benzenesulfonamide, 2-hydroxy- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

5-tert-butyl-2-methoxy-benzenesulfonamide (88085-79-4) → 2-hydroxybenzenesulfonamide (3724-14-9)

Guidance literature:

With aluminium trichloride; In xylene; at 55 - 60 ℃; for 24h;

DOI:10.1080/00397919408012644

Reference yield: 88.0%

→ Dibenzyl phosphite (17176-77-1) + 2-hydroxybenzenesulfonamide (3724-14-9)

Guidance literature:

Reference yield: 80.0%

→ 2-hydroxybenzenesulfonamide (3724-14-9)

Guidance literature:

upstream raw materials:

2-benzyloxy-benzenesulfonic acid amide

5-tert-butyl-2-methoxy-benzenesulfonamide

1-(tert-butyl)-4-methoxybenzene

3-(1,1-dimethylethyl)-6-methoxybenzenesulfonyl chloride

Downstream raw materials:

N-(2-hydroxy-benzenesulfonyl)-formimidic acid ethyl ester

3-benzyl-benzo[1,4,3]oxathiazine 1,1-dioxide

2-(2-Chloro-1,1,2-trifluoroethoxy)-benzenesulfonamide

2-allyloxy-benzenesulphonamide

Refernces

• 1、 -. "Method for catalytic synthesis of N-benzyl benzene sulfonamide compounds by boric acid/oxalic acid catalytic system under microwave radiation". Paragraph 0031; 0067. . Retrieved 2018/09/11.
• 2、 -. "Method and compositions for identifying anti-HIV therapeutic compounds". . . Retrieved 2008/06/13.