1-chloro-4-methyl-1-phenyl-2,3-dihydro-1H-phosphol-1-ium chloride

Base Information

• Chemical Name: 1-chloro-4-methyl-1-phenyl-2,3-dihydro-1H-phosphol-1-ium chloride
• CAS No.: 17786-49-1
• Molecular Formula: C₁₁H₁₃ClP*Cl
• Molecular Weight: 247.104
• Mol file: 17786-49-1.mol

Synonyms:1-chloro-4-methyl-1-phenyl-2,3-dihydro-1H-phosphol-1-ium chloride

Chemical Property of 1-chloro-4-methyl-1-phenyl-2,3-dihydro-1H-phosphol-1-ium chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-chloro-4-methyl-1-phenyl-2,3-dihydro-1H-phosphol-1-ium chloride

There total 4 articles about 1-chloro-4-methyl-1-phenyl-2,3-dihydro-1H-phosphol-1-ium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-chloro-3-methyl-1-phenylphosphol-3-enium chloride (104629-24-5) → 1-chloro-4-methyl-1-phenyl-2,3-dihydro-1H-phosphol-1-ium chloride (17786-49-1)

Guidance literature:

In chloroform; at 80 ℃; for 48h;

DOI:10.3762/bjoc.16.75

Reference yield:

3-Methyl-1-phenyl-2-phospholene 1-oxide (707-61-9) → 1-chloro-4-methyl-1-phenyl-2,3-dihydro-1H-phosphol-1-ium chloride (17786-49-1)

Guidance literature:

With oxalyl dichloride; In dichloromethane; at 20 ℃; for 1h; Schlenk technique; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.organomet.0c00788

Reference yield:

3-methyl-1-phenylphosphole (30540-42-2) → 1-chloro-4-methyl-1-phenyl-2,3-dihydro-1H-phosphol-1-ium chloride (17786-49-1) + 1-chloro-3-methyl-1-phenylphosphol-3-enium chloride (104629-24-5)

Guidance literature:

With hydrogenchloride; In dichloromethane-d2; at 0 ℃; for 48h; Title compound not separated from byproducts;

upstream raw materials:

Dichlorophenylphosphine

isoprene

3-methyl-1-phenylphosphole

1-chloro-3-methyl-1-phenylphosphol-3-enium chloride

Downstream raw materials:

4-methyl-1-phenyl-2,3-dihydro-1H-phosphole

1-benzyl-4-methyl-1-phenyl-2,3-dihydro-1H-phospholium; bromide

3-Methyl-1-phenyl-2-phospholene 1-oxide