3-[5-Methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-ylmethoxy]-benzaldehyde oxime

Base Information

Chemical Name:3-[5-Methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-ylmethoxy]-benzaldehyde oxime
CAS No.:174258-11-8
Molecular Formula:C₁₉H₁₅F₃N₂O₃
Molecular Weight:376.335
Hs Code.:

Synonyms:3-[5-Methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-ylmethoxy]-benzaldehyde oxime

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Chemical Property of 3-[5-Methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-ylmethoxy]-benzaldehyde oxime

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Technology Process of 3-[5-Methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-ylmethoxy]-benzaldehyde oxime

There total 3 articles about 3-[5-Methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-ylmethoxy]-benzaldehyde oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 174258-10-7
3-([5-methyl-2-(4-(trifluoromethyl)phenyl)oxazol-4-yl]methoxy)benzaldehyde

: 174258-11-8
3-[5-Methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-ylmethoxy]-benzaldehyde oxime

Guidance literature:: With hydroxylamine hydrochloride; sodium acetate; In ethanol; at 20 ℃;
DOI:10.1016/S0223-5234(00)01191-0

Reference yield:

: 100-83-4
meta-hydroxybenzaldehyde

: 174258-11-8
3-[5-Methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-ylmethoxy]-benzaldehyde oxime

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / dimethylformamide / 80 °C

2: HONH₂*HCl; aq. NaOAc / ethanol / 20 °C

With hydroxylamine hydrochloride; sodium acetate; potassium carbonate; In ethanol; N,N-dimethyl-formamide;
DOI:10.1016/S0223-5234(00)01191-0

Reference yield:

: 174258-39-0
4-(chloromethyl)-5-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-oxazole

: 174258-11-8
3-[5-Methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-ylmethoxy]-benzaldehyde oxime

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / dimethylformamide / 80 °C

2: HONH₂*HCl; aq. NaOAc / ethanol / 20 °C

With hydroxylamine hydrochloride; sodium acetate; potassium carbonate; In ethanol; N,N-dimethyl-formamide;
DOI:10.1016/S0223-5234(00)01191-0