4-chloro-n-butyric anhydride

Base Information

• Chemical Name: 4-chloro-n-butyric anhydride
• CAS No.: 20496-01-9
• Molecular Formula: C₈H₁₂Cl₂O₃
• Molecular Weight: 227.087
• Mol file: 20496-01-9.mol

Synonyms:4-chloro-n-butyric anhydride

Chemical Property of 4-chloro-n-butyric anhydride

Chemical Property:

• Boiling Point: 106-109 °C(Press: 4-5 Torr)
• Density: 1.234±0.06 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

4-Chlorobutyricanhydride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-chloro-n-butyric anhydride

There total 3 articles about 4-chloro-n-butyric anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

→ 4-chloro-n-butyric anhydride (20496-01-9)

Guidance literature:

With magnesium basic carbonate; di-tert-butyl dicarbonate; at 25 ℃; for 6h;

Reference yield: 88.0%

4-Chlorobutanoyl chloride (4635-59-0) → 4-chloro-n-butyric anhydride (20496-01-9)

Guidance literature:

With acetic anhydride; at 95 ℃; for 3h;

DOI:10.1246/bcsj.60.1161

Reference yield:

γ-chlorobutyric acid (627-00-9) + acetic anhydride (108-24-7) → 4-chloro-n-butyric anhydride (20496-01-9)

Guidance literature:

Heating;

upstream raw materials:

γ-chlorobutyric acid

acetic anhydride

4-Chlorobutanoyl chloride

Downstream raw materials:

N-(4-phenylthiazol-2-yl)-4-chlorobutanamide

4-butanolide

1(2H)-acenaphthylenone

acenaphthene