1-(3-((tert-butyldimethylsilyloxy)methyl)phenyl)-2,2,2-trifluoroethanone oxime

Base Information

Chemical Name:1-(3-((tert-butyldimethylsilyloxy)methyl)phenyl)-2,2,2-trifluoroethanone oxime
CAS No.:162844-88-4
Molecular Formula:C₁₅H₂₂F₃NO₂Si
Molecular Weight:333.426
Hs Code.:

Synonyms:1-(3-((tert-butyldimethylsilyloxy)methyl)phenyl)-2,2,2-trifluoroethanone oxime

Suppliers and Price of 1-(3-((tert-butyldimethylsilyloxy)methyl)phenyl)-2,2,2-trifluoroethanone oxime

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(3-((tert-butyldimethylsilyloxy)methyl)phenyl)-2,2,2-trifluoroethanone oxime

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(3-((tert-butyldimethylsilyloxy)methyl)phenyl)-2,2,2-trifluoroethanone oxime

There total 5 articles about 1-(3-((tert-butyldimethylsilyloxy)methyl)phenyl)-2,2,2-trifluoroethanone oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 176640-03-2
1-(3-((tert-butyldimethylsilyloxy)methyl)phenyl)-2,2,2-trifluoroethanone

: 162844-88-4
1-(3-((tert-butyldimethylsilyloxy)methyl)phenyl)-2,2,2-trifluoroethanone oxime

Guidance literature:: With pyridine; hydroxylamine hydrochloride; In ethanol; at 80 ℃;
DOI:10.1016/j.chembiol.2019.03.008

Reference yield:

: 15852-73-0
(3-Bromophenyl)methanol

: 162844-88-4
1-(3-((tert-butyldimethylsilyloxy)methyl)phenyl)-2,2,2-trifluoroethanone oxime

Guidance literature:: Multi-step reaction with 3 steps

1.1: dmap; triethylamine / dichloromethane / 3 h / 0 - 20 °C

2.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C

2.2: 2 h / -78 °C

3.1: hydroxylamine hydrochloride; pyridine / ethanol / 3 h / Reflux

With pyridine; dmap; n-butyllithium; hydroxylamine hydrochloride; triethylamine; In tetrahydrofuran; ethanol; hexane; dichloromethane;

Reference yield:

: 103978-12-7
[(3-bromobenzyl)oxy](tert-butyl)dimethylsilane

: 162844-88-4
1-(3-((tert-butyldimethylsilyloxy)methyl)phenyl)-2,2,2-trifluoroethanone oxime

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C

1.2: 2 h / -78 °C

2.1: hydroxylamine hydrochloride; pyridine / ethanol / 3 h / Reflux

With pyridine; n-butyllithium; hydroxylamine hydrochloride; In tetrahydrofuran; ethanol; hexane;